医学研究与教育 ›› 2013, Vol. 30 ›› Issue (1): 48-50.

• 临床研究 • 上一篇    下一篇

2型糖尿病胰岛素泵强化治疗疗效观察及其临床应用影响因素

刘丽敏   

  1. 保定市第二医院急诊科,河北 保定 071000
  • 收稿日期:2016-10-09 修回日期:2016-10-09 出版日期:2013-02-25 发布日期:2013-02-25

Clinical observation and its clinical influencing factors on insulin pump intensive treatment of type 2 diabetes mellitus

  • Received:2016-10-09 Revised:2016-10-09 Online:2013-02-25 Published:2013-02-25

摘要: 目的比较胰岛素泵与传统疗法治疗2型糖尿病的疗效及其影响因素.方法将50例2型糖尿病患者(都经过OGTT及胰岛素C肽测定确诊)住院期间分成胰岛素泵强化治疗组与皮下多次胰岛素注射治疗(传统疗法)两组进行疗效观察,分别监测治疗前后空腹血糖、餐前0.5 h血糖、餐后2 h血糖值,进行组间比较.结果胰岛素泵组与皮下胰岛素注射组比较,血糖控制优于每日多次胰岛素注射组.胰岛素泵与传统疗法治疗糖尿病的疗效比较:入院时空腹血糖、餐后血糖胰岛素泵组与传统疗法组比较差异均无统计学意义(P>0.05).治疗后两组进行比较无论是空腹血糖值、餐前血糖值、餐后血糖值差异均有统计学意义(P<0.01).结论胰岛素泵能模拟人生理胰岛素分泌,有效控制血糖,大大改善糖尿病患者的生活质量.

关键词: 胰岛素泵, 2型糖尿病, 多次胰岛素注射

Abstract: Objective To compare the efficacy and its influencing factors of insulin pump treatment with traditional insulin pump therapy in the treatment of type 2 diabetes mellitus. Methods Fifty Type 2 diabetic subjects (after OGTT and insulin c-peptide measurement diagnose) were randomized to treat with continuous subcutaneous infusion pump (CSII) and multiple daily insulin injections (MDI), FPG, 0.5 h PG and 2 h PG value was compared between groups before and after treatment respectively. Results There were no significant difference on the FPG and postprandial blood glucose between insulin pump group and the traditional therapy group before admission (P>0.05). Whether the FPG value, pre-dinner blood glucose value, or postprandial blood sugar value, there were not significant difference between the two groups after treatment (P<0.01). Conclusion Insulin pump can simulate human physiological insulin secretion, control the blood glucose level effectively, greatly improve the life quality of patients with diabetes.

Key words: insulin pump, type 2 diabetes mellitus, multiple insulin injections

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