医学研究与教育 ›› 2024, Vol. 41 ›› Issue (1): 27-33.DOI: 10.3969/j.issn.1674-490X.2024.01.004

• 临床医学 • 上一篇    下一篇

疼痛干预在急性心肌梗死中的综合效应

江永正1,梁天乐2,贾辛未2   

  1. 1. 徐州市贾汪区人民医院心血管内科, 江苏 徐州 221011;
    2. 河北大学附属医院心血管内科, 河北 保定 071000
  • 收稿日期:2022-08-23 出版日期:2024-02-25 发布日期:2024-02-25
  • 通讯作者: 贾辛未(1967—),男,河北保定人,教授,博士,博士生导师,主要从事心内科疑难病及危重症的处理、冠心病的介入治疗及心脏起搏治疗。E-mail: jxw1967@126.com
  • 作者简介:江永正(1989—),男,江苏徐州人,主治医师,硕士,主要从事冠状动脉介入和心血管常见病的诊疗。 E-mail: jiangyongzheng@126.com

  • Received:2022-08-23 Online:2024-02-25 Published:2024-02-25

摘要: 急性心肌梗死作为冠状动脉疾病最严重的情况常伴有剧烈的胸痛,疼痛不仅降低了患者的治疗依从性,而且通过增加心肌耗氧、加重心脏负荷、诱发冠状动脉血管痉挛加重病情。因此,及时干预剧烈胸痛在急性心肌梗死的治疗中至关重要。现就急性心肌梗死疼痛发生机制、阿片类药物以及非甾体抗炎药在急性心肌梗死中的应用进行综述。

关键词: 急性心肌梗死, 阿片, 非甾体抗炎药, 疼痛, 心肌保护, 抗血小板

Abstract: Acute myocardial infarction, as the most severe condition of coronary artery disease, is often accompanied by severe chest pain, which not only reduces the patient's treatment compliance, but also worsens the condition by increasing myocardial oxygen consumption, increasing cardiac load, and inducing coronary vasospasm. Therefore, timely intervention of severe chest pain is essential in the treatment of acute myocardial infarction. This article reviews the mechanism of pain in acute myocardial infarction, the use of opioids and non-steroidal anti-inflammatory drugs in acute myocardial infarction.

Key words: acute myocardial infarction, opioids, non-steroidal anti-inflammatory drugs, pain, myocardial protection, antiplatelet

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