Abstract: Objective To evaluate the effects of passive smoking on postoperative hypoxemia(POH)of on-pump coronary artery bypass grafting surgery patients. Methods 126 patients were undergone on-pump CABG surgery.The patients were divided into non-smokers and passive smokers, the latter were further divided into the following 3 sub-groups according to exposure time:<10 h per week,10-20 h and >20 h per week. The primary outcome measure was the incidence of POH after CABG surgery in each group. Secondary outcomes included length of postoperative mechanical ventilation and ICU stay. Logistic analysis was used to observe the relationship between passive smoking and postoperative hypoxemia. Results There was a significant difference in the incidence of POH in the 4 groups(P<0.01),The incidence of hypoxemia(20.00%, 25.93%, 55.56% and 59.26%, respectively)in each group increased successively. The length of postoperative mechanical ventilation and ICU stay were longer in passive smokers than that in non-smokers(P<0.05). Conclusion Passive smoking is a risk factor of POH after CABG surgery, passive smoking can increase POH incidence after on-pump CABG surgery,and it also can prolong the length of postoperative mechanical ventilation and ICU stay. With the increase of exposure time, the incidence of POH also shows increasing trend.

Key words: passive smoking, coronary artery bypass grafting, on-pump, hypoxemia