[1] BENDELAC A, SAVAGE P B, TEYTON L.The biology of NKT cells[J].Annu Rev Immunol,2007, 25:297-336.DOI:10.1146/annurev.immunol.25.022106.141711.
[2] ROSSJOHN J, PELLICCI D G, PATEL O.Recognition of CD1d-restricted antigens by natural killer T cells[J].Nat Rev Immunol,2012,12:845-857.DOI:10.1038/nri3328.
[3] KAWANO T.CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides[J].Science,1997, 278:1626-1629.
[4] CUI J.Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors[J].Science,1997, 278:1623-1626.
[5] HNISZ D.Super-enhancers in the control of cell identity and disease[J].Cell,2013, 155:934-947.DOI:10.1016/j.cell.2013.09.053.
[6] KOUZARIDES T.Chromatin modifications and their function[J].Cell,2007, 128:693-705.DOI:10.1016/j.cell.2007.02.005.
[7] RADA-IGLESIAS A.A unique chromatin signature uncovers early developmental enhancers in humans[J].Nature,2011, 470:279-283.
[8] BERNSTEIN B E.A bivalent chromatin structure marks key developmental genes in embryonic stem cells[J].Cell,2006, 125:315-326.
[9] NORTHRUP D, YAGI R, CUI K, et al.Histone demethylases UTX and JMJD3 are required for NKT cell development in mice[J].Cell & Bioscience, 2017, 7(1):25.DOI:10.1038/nature06145.
[10] CREYGHTON M P.Histone H3K27ac separates active from poised enhancers and predicts developmental state[J].Proc Natl Acad Sci U S A,2010, 107:21931-21936.DOI:10.1073/pnas.1016071107.
[11] SIMON J A, KINGSTON R E.Mechanisms of polycomb gene silencing: knowns and unknowns[J].Nat Rev Mol Cell Biol,2009, 10:697-708.DOI:10.1038/nrm2763.
[12] MILLER S A, MOHN S E, WEINMANN A S.Jmjd3 and UTX play a demethylaseindependent role inchromatin remodeling to regulate T-box family member-dependent gene expression[J]. Mol Cell, 2010,40(4): 594-605.
[13] XU J, DENG X, WATKINS R, et al.Sex-specific Differences in Expression of Histone Demethylases Utx and Uty in Mouse Brain and Neurons[J].Journal of Neuroscience the Official Journal of the Society for Neuroscience, 2008, 28(17):4521.DOI:10.1523/JNEUROSCI.5382-07.2008.
[14] AGGER K, CLOOS P A, CHRISTENSEN J, et al.UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development[J].Nature, 2007, 449(7163): 731-734.DOI:10.1038/nature06145.
[15] LEE M G, VILLA R, TROJER P, et al.Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination [J].Science, 2007, 318(5849): 447-450.
[16] DE SANTA F, TOTARO M G, PROSPERINI E, et al.The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing[J].Cell, 2007, 130(6): 1083-1094.
[17] HONG S, CHO Y W, YU L R, et al.Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases [J].Proc Natl Acad Sci U S A, 2007,104(47): 18439-18444.DOI:10.1073/pnas.0707292104.
[18] 郭晓强, 陆菁潇, 桂耀庭, 等.组蛋白H3K27 去甲基化酶与肿瘤发生[J].中国生物化学与分子生物学报,2011, 27(8): 706-711.
[19] DASHTSOODOL N, SHIGEURA T, AIHARA M, et al.Alternative pathway for the development of V[alpha] 14+ NKT cells directly from CD4-CD8-thymocytes that bypasses the CD4+CD8+ stage[J].Nature Immunology, 2017, 18(3):274.
[20] GAPIN L.Development of invariant natural killer T cells[J].Current Opinion in Immunology, 2016, 39:68.DOI:10.1016/j.coi.2016.01.001.
[21] SEILER M P, MATHEW R, LISZEWSKI M K, et al.Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling[J].Nature Immunology, 2012, 13(3):264.DOI:10.1038/ni0413-413d.
[22] SAVAGE A K, CONSTANTINIDES M G, HAN J, et al.The transcription factor PLZF directs the effector program of the NKT cell lineage[J].Immunity, 2008, 29(3):391.
[23] KIM P J, PAI S Y, BRIGL M, et al.GATA-3 regulates the development and function of invariant NKT cells[J].Journal of Immunology, 2006, 177(10):6650-6659.
[24] YUE XIAOJING, ANA I, TILMAN B, et al.Essential role of Mediator subunit Med1 in invariant natural killer T-cell development[J].PNAS, 2011, 108(41): 17105-17110.DOI:10.1073/pnas.1109095108.
[25] MATSUDA J L, ZHANG Q, NDONYE R, et al.T-bet concomitantly controls migration, survival, and effector functions during the development of Va14i NKT cells[J].Blood,2006, 107(7):2797-2805.
[26] STRADNER M H, ChEUNG K P, LASORELLA A, et al.Id2 regulates hyporesponsive invariant natural killer T cells[J].Immunol Cell Biol, 2016, 94(7): 640-645.DOI:10.1038/icb.2016.19.
[27] ADORO S, MCCAUGHTRY T, ERMAN B, et al.Coreceptor gene imprinting governs thymocyte lineage fate[J].Embo Journal, 2012, 31(2):366.DOI:10.1038/emboj.2011.388.
[28] BEYAZ S, JI H K, PINELLO L, et al.The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells[J].Nature Immunology, 2017, 18(2):184.DOI:10.1038/ni.3644.
[29] KROVI S H, GAPIN L.iNKT cells need UTX-tra demethylation[J].Nature Immunology, 2017, 18(2):148.DOI:10.1038/ni.3663. |
