化浊解毒软肝方联合熊去氧胆酸治疗原发性胆汁性肝硬化

医学研究与教育 ›› 2013, Vol. 30 ›› Issue (1): 57-61.

化浊解毒软肝方联合熊去氧胆酸治疗原发性胆汁性肝硬化

靳红燕¹,李佃贵²,王彦刚²,钱金花²

1.河北大学研究生学院,河北保定 071000
2.河北省中医院,河北石家庄 050001

收稿日期:2016-10-09 修回日期:2016-10-09 出版日期:2013-02-25 发布日期:2013-02-25

Clinical efficacy of Huazhuojieduruanganfang combined with ursodeoxycholic acid in treating 60 cases with primary biliary cirrhosis

Received:2016-10-09 Revised:2016-10-09 Online:2013-02-25 Published:2013-02-25

摘要/Abstract

摘要： 目的观察化浊解毒软肝方治疗原发性胆汁性肝硬化患者症状及生化指标的影响.方法将60例原发性胆汁性肝硬化患者随机分为两组,对照组30例予口服熊去氧胆酸(优思弗)治疗;治疗组30例在对照组的基础上加服化浊解毒软肝方(基本方:田基黄、茵陈、虎杖、绞股蓝、黄连、黄柏、鳖甲、山甲珠、当归、白芍、红景天)治疗,观察化浊解毒软肝方对原发性胆汁性肝硬化患者症状及生化指标的影响,观察治疗前后的生化指标变化.结果治疗组在生化指标方面的改善明显优于对照组,差别有统计学意义(P<0.05).结论化浊解毒软肝方治疗原发性胆汁性肝硬化患者生化指标可显著降低.

关键词: 化浊解毒软肝方, 中西医结合疗法, 原发性胆汁性肝硬化, 生化指标

Abstract: Objective To observe the effects on cholestasis indicators of Huazhuo Jiedu Ruangan decoction in patients with primary biliary cirrhosis. Methods 60 cases of patients with primary biliary cirrhosis were randomly divided into two groups, the patients of the control group oraled ursodeoxycholic acid (UDCA);the patients of the treatment group taken Huazhuo Jiedu Ruangan decoction beside UDCA. The effects on cholestasis indicators of Huazhuo Jiedu Ruangan decoction in patients with primary biliary cirrhosis, and the biochemical indicators of cholestasis before and after the treatment were observed. Results The results showed that biochemical indicators in the treatment group improved significantly better than that of the control group, the difference was significant (P<0.05). Conclusion Cholestasis indicators of the patients with primary biliary cirrhosis treated with Huazhuo detoxification decrease significantly.

Key words: Huazhuo Jiedu Ruangan decoction, integrative medicine, primary biliary cirrhosis, biochemical indicator

中图分类号:

R256.4

靳红燕,李佃贵,王彦刚,钱金花. 化浊解毒软肝方联合熊去氧胆酸治疗原发性胆汁性肝硬化[J]. 医学研究与教育, 2013, 30(1): 57-61.

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