Abstract: Acute ST-segment elevation myocardial infarction(STEMI)is the cause of death for patients with cardiovascular disease worldwide, for which timely and effective opening of infarct related vessels is the most important treatment. Early restoration of culprit vessel patency by primary percutaneous coronary intervention(PCI)represents the reperfusion strategy of choice for patients with STEMI. However, about half of the patients still cannot get sufficient blood perfusion to the distal coronary microvasculature after PCI, which is closely related to the occurrence of adverse cardiovascular events. This situation is called no-reflow phenomenon(NRP). This article reviews recent treating progress of drug therapy and non-drug therapy for NRP after PCI.

Key words: acute ST-segment elevation myocardial infarction, percutaneous coronary intervention, no-reflow phenomenon, treatment progress

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