Changes of serum cortisol level and its prognosis in full term infants with asphyxia

doi:10.3969/j.issn.1674-490X.2013.04.009

Abstract

Abstract: Objective To observe the effects of different degree of asphyxia on cortisol levels change in full term infants’ serum cortisol levels as the monitoring indicators. Methods 90 full term infants were selected, 28 cases with mild asphyxia and 32 cases with severe asphyxia, 30 cases with no suffocation as the control group. 2mL venous blood was collected to test the serum cortisol levels within 24 hours and a week after birth. Results (1) Serum cortisol of full-term infants with mild asphyxia and severe asphyxia was obviously different in 24 hours and 7days after birth. (2) The difference of serum cortisol was obvious in 24 hours after birth between group with mild asphyxia and the control group, while it became subtle in a week. (3) The difference of serum cortisol was obvious both in 24 hours and a week after birth between group with severe asphyxia and the control group. Conclusion Full-term infants have already perfect adrenal cortex function, and serum cortisol levels are related to the asphyxia degree.

Key words: full term infants, aphyxia, cortisol

CLC Number:

ZHU Weina,YANG Mei,HE Xin,MA Jing. Changes of serum cortisol level and its prognosis in full term infants with asphyxia[J]. Medical Reserch and Education, 2013, 30(4): 32-35.

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