Medical Reserch and Education ›› 2014, Vol. 31 ›› Issue (5): 68-72.

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Research on post-stroke depression with hyperhomocysteinemia

GAO Tianchu1, LI Huimin2, LIU Xiyan1, SHI Fuping2   

  1. 1. Health Science Center, Hebei University, Baoding 071000, China; 2. Department of Neurology, Affiliated Hospital of Hebei University, Baoding 071000, China
  • Online:2014-10-25 Published:2014-10-25

Abstract: One third of all stroke survivors develop post-stroke depression(PSD). It’s negatively impacts stroke outcome with increased morbidity, mortality and poorer functional recovery. Accumulating data suggest that hyperhomocysteinemia(HHcy) be associated with the risk of stroke in the general population, but the relationship remains unclear in PSD patients. In recent years, there have been a lot of studies on the correlation between them in many aspects (such as epidemiology, pathophysiology, clinical manifestation, diagnosis, and biological treatment), which has aroused wide concern.

Key words: post-stroke depression(PSD), hyperhomocysteinemia(HHcy), clinical research

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