The role of innate immune response during infection of Brucella

doi:10.3969/j.issn.1674-490X.2015.03.018

Abstract

Abstract: Brucella is a Gram-negative, facultative intracellular bacteria, which includes Brucella. abortus(cattle), B.melitensis(goats), B.suis (swine), B.canis(dogs) and Brucella infected by marine mammals,et al. B.abortus, B.melitensis, B.suis and B.canis, et al can invade into humans and animals through a variety of ways and cause Brucellosis that is a severe zoonotic desease. The innate immune system is the first line of defensing against the infection of pathogen for our organism, which plays a key role during the infection of Brucella. This paper overviews the role of innate immune response during the infection of Brucella.

Key words: Brucella, Brucellosis, innate immune, pattern-recognition receptor, pathogen-associated molecular pattern

CLC Number:

R392

GAO Wei, WANG Meng, CAO Zhiran. The role of innate immune response during infection of Brucella[J]. Medical Reserch and Education, 2015, 32(3): 82-86.

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