doi:10.3969/j.issn.1674-490X.2024.01.002

Abstract

Abstract: It has been shown that the human gut is settled with a large microbiota, which is involved in the regulation of the body's immune homeostasis and is closely related to the development of ischaemic stroke. The discovery of the microbial-gut-brain axis links the gut to the brain and plays an important role in human health and disease processes. This paper reviews the regulatory mechanisms of the microbial-gut-brain axis, the modulation of gut flora and its metabolites after stroke, and the possible mechanisms of the brain-gut axis based on brain and gut immune responses after ischaemic stroke. These studies provide important implications for exploring new directions of gut and brain immunotherapy after stroke and improving stroke prognosis.

Key words: ischaemic stroke, gut flora, microbe-gut-brain axis, immunity

CLC Number:

References

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[1]	. [J]. Journal of Hebei Medical College for Continuing Education, 2022, 39(6): 9-14.
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