Abstract: More and more evidences indicate that hypertension and end-organ damage of hypertension can be mediated not only by hemodynamic injury, but also by inflammation. Inflammation plays an important role in the pathophysiology of hypertension and mediates various complications by activating the immune response in the body. Complement, as a potential regulator of hypertension and the intersection of innate immunity and adaptive immunity, affects the occurrence and development of hypertension through both innate immunity and adaptive immunity. In this paper, we will review the interaction between complement and T lymphocytes in acquired immune cells during the occurrence and development of hypertension, in order to better understand the relationship between complement and hypertension, and provide new ideas for disease diagnosis and treatment.

Key words: hypertension, complement, T lymphocytes, adaptive immunity

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