人胚胎干细胞分化研究进展

doi:10.3969/j.issn.1674-490X.2009.02.038

医学研究与教育 ›› 2009, Vol. 26 ›› Issue (2): 88-91,94.DOI: 10.3969/j.issn.1674-490X.2009.02.038

人胚胎干细胞分化研究进展

邸科前¹,王晶晶²,张宏馨¹

1.河北大学医学部,河北,保定,071000
2.华北油田井下医院,河北,任丘,062552

收稿日期:2016-10-09 修回日期:2016-10-09 出版日期:2009-04-25 发布日期:2009-04-25

Received:2016-10-09 Revised:2016-10-09 Online:2009-04-25 Published:2009-04-25

摘要/Abstract

摘要： 胚胎干细胞(Embryonic Stem Cell,ES细胞)是由着床前囊胚期内细胞团(Inner Cell Mass,ICM)或早期胚胎原始生殖嵴的胚胎生殖细胞(Primordial Germ Cells,PGCs)建立的、可在体外未分化状态下长期增殖传代的、具有稳定的二倍体核型和多能干细胞表面特异抗原标记的、可分化为3个胚层来源的各种组织和细胞类型(包括生殖腺和生殖细胞)的永久细胞系.基于其特性,目前普遍认为,.ES细胞对体外研究动物和人胚胎的发生发育,新基因的发现,药物的筛选和致畸实验及作为细胞组织移植治疗,克隆治疗和基因治疗的细胞源及产生克隆和转基因动物等领域将产生重要的影响.本文综述了人胚胎干细胞诱导分化研究进展.

中图分类号:

Q254

邸科前,王晶晶,张宏馨. 人胚胎干细胞分化研究进展[J]. 医学研究与教育, 2009, 26(2): 88-91,94.

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人胚胎干细胞分化研究进展

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