丙种球蛋白在重症手足口病患儿中的应用

doi:10.3969/j.issn.1674-490X.2015.05.001

医学研究与教育 ›› 2015, Vol. 32 ›› Issue (5): 1-3.DOI: 10.3969/j.issn.1674-490X.2015.05.001

• 临床研究 • 下一篇

丙种球蛋白在重症手足口病患儿中的应用

马士恒，李明

河北大学附属医院感染性疾病科，河北保定 071000

出版日期:2015-10-25 发布日期:2015-10-25
作者简介:马士恒（1968— ），男，河北博野人，主任医师，硕士，主要从事感染性疾病的诊治及教学工作。E-mail: mashiheng@126.com

Effects of intravenous immunoglobulin in children with severe hand-foot-mouth disease

MA Shiheng, LI Ming

Department of Infectious Diseases, Affiliated Hospital of Hebei University, Baoding 071000, China

Online:2015-10-25 Published:2015-10-25

摘要/Abstract

摘要： 目的探讨静脉丙种球蛋白治疗重症手足口病的临床疗效。方法总结收治的 59 例重症手足口病患儿的病历资料，应用静脉丙种球蛋白治疗的患儿为治疗组；其余未应用丙种球蛋白的患儿为对照组，比较 2 组的临床效果。结果治疗组的热退、皮疹消退、神经系统症状消退以及住院时间分别为（4.52±1.41）d、（6.35±1.93）d、（4.06±1.25）d、（9.94±2.14）d，对照组分别为（5.78±1.12）d、（8.03±2.74）d、（5.53±1.50）d、（11.31±2.05）d。2 组比较均为 P<0.05，差异有统计学意义。结论重症手足口病患儿应用静脉丙种球蛋白是安全有效的。

关键词: 手足口病, 静脉丙种球蛋白, 重症患者

Abstract: Objective To study the effects of intravenous immunoglobulin in children with severe hand-foot-mouth disease (HFMD). Methods The medical records of 59 children with severe hand-foot-mouth disease were reviewed. Children with intravenous immunoglobul in therapy were selected as treatment group,the others as control group. Effects of two groups were compared. Results Pyretolysis time, the skin rash regression time, the nervous system symptoms disappeard time, and hospital stays in treatment group were (4.52±1.41)d, (6.35±1.93)d, (4.06±1.25)d, (9.94±2.14)d, respectively, in control group were (5.78±1.12)d, (8.03±2.74)d, (5.53±1.50)d, (11.31±2.05)d, respectively. They were shorter in treatment group than that in control group (P<0.05). Conclusion Intravenous immunoglobulin was safe and effective in children with severe hand-foot-mouth disease.

Key words: hand-foot-mouth disease, intravenous immunoglobulin, critical patients

中图分类号:

马士恒，李明. 丙种球蛋白在重症手足口病患儿中的应用[J]. 医学研究与教育, 2015, 32(5): 1-3.

MA Shiheng, LI Ming. Effects of intravenous immunoglobulin in children with severe hand-foot-mouth disease[J]. Medical Reserch and Education, 2015, 32(5): 1-3.

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丙种球蛋白在重症手足口病患儿中的应用

Effects of intravenous immunoglobulin in children with severe hand-foot-mouth disease

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