医学研究与教育 ›› 2015, Vol. 32 ›› Issue (6): 61-64.DOI: 10.3969/j.issn.1674-490X.2015.06.014

• 疾病预防控制 • 上一篇    下一篇

承德地区女性生殖道支原体感染与细菌性阴道病的相关研究

周亮1,韩媛媛1,罗婧梅1,陈怡橙1,冯柯青1,杜娈英1,吴晓玲2   

  1. 1. 承德医学院,河北 承德 067000;2. 承德市妇幼保健院,河北 承德 067000
  • 出版日期:2015-12-25 发布日期:2015-12-25
  • 通讯作者: 杜娈英(1963—),女,河北保定人,教授,硕士生导师。主要从事病原生物学教学和研究工作。 E-mail: Luanying@126.com
  • 作者简介:周亮(1993—),女,河北沧州人。E-mail: 2536116057@qq.com
  • 基金资助:
    河北省计划生育委员会课题(2010-A07)

Investigation on the correlation of genital mycoplasma infection with bacterial vaginal in Chengde area

ZHOU Liang1, HAN Yuanyuan1, LUO Jingmei1, CHEN Yicheng1, FENG Keqing1, DU Luanying1, WU Xiaoling2   

  1. 1. Chengde Medical University, Chengde 067000, China; 2. Chengde Maternal and Child Health-Care Hospital, Chengde 067000, China
  • Online:2015-12-25 Published:2015-12-25

摘要: 目的 了解承德地区女性生殖道支原体(Mycoplasma)感染情况,探讨承德地区女性生殖道支原体感染与细菌性阴 道病(bacterial vaginal,BV)的关系。方法2015 年 6 月至 2015 年 9 月采集女性阴道后穹隆分泌物并填写相关调查问卷, 利用核酸(DNA)提取、聚合酶链式反应(PCR)、琼脂糖凝胶电泳实验技术检测解脲支原体(Ureaplasma urealyticum, Uu)、人型支原体(Mycoplasma hominis,Mh)的感染情况,结合调查问卷讨论支原体感染对细菌性阴道病的影响。结果 纳入合格标本 715 份,其中解脲支原体感染 285 份,占 39.86%,人型支原体感染 142 份,占 19.86%;支原体感染中细菌 性阴道病 125 份,占 55.31%。结论 OR=4.37>1,推断解脲支原体和人型支原体感染是女性患细菌性阴道病的危险因素。

关键词: 解脲支原体, 人型支原体, 细菌性阴道病

Abstract: Objective To understand femal genital infection situation of mycoplasma in Chengde area ,thus to investigate the correlation of women genital Mycoplasma infection with bacterial vaginal(BV). Methodsquestionnaire was conducted. The nucleic acid(DNA) extraction and polymerase chain reaction (PCR) were used and agarose gel electrophoresis experimental technologies were applied to detect the infection of ureaplasma urealyticum(Uu) and mycoplasma hominis(Mh),and the influences between genital mycoplasma infection and bacterial vaginal were analyzed by considering the results of the questionnaire. ResultsOf 715 specimens, 285 people were infected with Uu, accounting for 39.86%. 142 people were infected with Mh, accounting for 19.86%. In all the people infected with mycoplasma, 125 were infected with bacterial vaginal, accounting for 55.31%. Conclusion OR=4.37>1, the results suggest that Uu and Mh infection could be the risk factor for women suffering from bacterial vaginosis

Key words: mycoplasma hominis, ureaplasma urealyticum, bacterial vaginal

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