医学研究与教育 ›› 2019, Vol. 36 ›› Issue (6): 28-31.DOI: 10.3969/j.issn.1674-490X.2019.06.005

• 临床医学 • 上一篇    下一篇

肝血流动力学变化与吲哚菁绿代谢试验评价肝储备功能的对比

韩志钧1,韩柠泽2,闫伟3,马金彤1   

  1. 1.保定市传染病医院功能科, 河北 保定 071000;
    2.北京儿童医院保定医院眼科, 河北 保定 071000;
    3.保定市妇幼保健院手术室, 河北 保定 071000
  • 收稿日期:2019-09-11 出版日期:2019-12-25 发布日期:2019-12-25
  • 作者简介:韩志钧(1973—),男,河北保定人,副主任医师,主要从事超声诊断工作,擅长肝炎、脂肪肝、肝硬化、肝肿瘤彩色多普勒超声诊断及鉴别诊断。 E-mail: 13082392668@163.com

  • Received:2019-09-11 Online:2019-12-25 Published:2019-12-25

摘要: 目的 应用彩超检测肝血流动力学替代吲哚菁绿代谢试验。研究肝硬化肝固有动脉阻力指数(resistance index,RI)、门静脉充血指数(congestion index,CI)、门静脉血流量(quantity of portal venous,QPV)与肝储备功能的关系。方法 2015年12月至2019年1月,120例肝硬化患者,按肝功能Child-Pugh分级分为A、B、C级,健康对照组40例。彩超检测肝固有动脉RI、CI、QPV与吲哚菁绿15 min滞留率(indocyanine green at 15 min,ICGR15)对照。结果 RI、CI、QPV与ICGR15评价肝储备功能一致,Child-Pugh评分与RI、CI、QPV、ICGR15呈正相关。结论 RI、CI、QPV准确评价肝储备功能,是替代Child-Pugh分级、吲哚菁绿简便易行方法。

关键词: 彩色多普勒, 肝血流动力学, 肝储备功能

Abstract: Objective To study the correlation among resistance index of proper hepatic artery(RI), congestion index(CI), quantity of portal venous(QPV)and hepatic function reserve among patients with hepatic cirrhosis during different pathological stages. Methods 120 cases of hepatic cirrhosis were examined as study subjects, who were divided into Levels A B and C according to Child-Pugh with healthy subjects chosen as control group. Color Doppler ultrasonography and ICGR15.were applied to test RI, CI and QPV. Results The results showed that there were positively correlations among RI, CI, as well as QPV with ICGR15 in patients with cirrhosis. Base on the Child-Pugh score to evaluate hepatic function, RI,CI, QPV, and ICGR15 were positively correlated with Child-Pugh scores. Conclusion RI, CI and QPV are simple and easy methods to evaluate liver reserve function instead of child Pugh classification and indocyanine green.

Key words: color doppler ultrasonography, hepatic hemodynamics, hepatic function reserve

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