医学研究与教育 ›› 2021, Vol. 38 ›› Issue (4): 29-33.DOI: 10.3969/j.issn.1674-490X.2021.04.005

• 临床医学 • 上一篇    下一篇

康复新液湿敷治疗面部激素依赖性皮炎的效果

罗丁,张胜逆,沈俊萍,刘春梅,丁秋允   

  1. 河北大学附属医院皮肤科, 河北 保定 071000
  • 收稿日期:2021-03-08 出版日期:2021-08-25 发布日期:2021-08-25
  • 通讯作者: 丁秋允(1964—),女,河北保定人,主任医师,主要从事免疫性皮肤病相关研究。E-mail: dingqiuyun888@sina.com
  • 作者简介:罗丁(1992—),男,河北保定人,医师,硕士,主要从事变态反应性皮肤病相关研究。 E-mail: 406815424@qq.com

  • Received:2021-03-08 Online:2021-08-25 Published:2021-08-25

摘要: 目的 探讨康复新液外敷疗法对面部激素依赖性皮炎的治疗效果。方法 门诊收集共96例激素依赖性皮炎患者资料,其中48例患者使用康复新液局部冷敷,48例患者使用生理盐水冷敷,比较2组患者的治疗效果。结果 通过对2组的评分比较分析来看,不同时间的评分差异有统计学意义(F=16.340,P<0.001),2组间的差异有统计学意义(F=12.785,P<0.001),治疗后康复新液组评分显著低于生理盐水组。康复新液组48例患者中39例痊愈、显效8例、好转1例;生理盐水组36例痊愈、显效10例、2例好转,2组疗效差异无统计学意义(Z=0.765,P>0.05)。康复新液组治疗后1个月、3个月、6个月复发率分别为4.17%,6.25%,10.42%,生理盐水组复发率分别为18.75%、25.00%、35.42%,2组复发率比较差异有统计学意义(P<0.05)。结论 康复新液外敷治疗激素依赖性皮炎疗效肯定,并能减少该病的复发。

关键词: 激素依赖性皮炎, 康复新液, 生理盐水

Abstract: Objective To explore the therapeutic effect of Kangfuxin solution external application in the treatment of facial hormone-dependent dermatitis. Methods A total of 96 patients with hormone-dependent dermatitis were collected in the outpatient department. Of those, 48 patients were given a local cold compress with Kangfuxin solution and the others were given a cold compress with normal saline. The treatment effects of the two groups were compared. Results Through the comparison and analysis of the scores of the two groups, the difference in scores at different times was statistically significant(F=16.340, P<0.001), and the difference between the two groups was statistically significant(F=12.785, P<0.001).The score of Kangfuxinye group was significantly higher than that of normal saline group. Of the 48 patients in the Kangfuxinye group, 39 were cured, 8 cases were markedly effective, and 1 case improved; in the normal saline group, 36 cases were cured, 10 cases were markedly effective, and 2 cases improved. There was no statistically significant difference in efficacy between the two groups(Z=0.765, P>0.05). The recurrence rates observed in the Kangfuxinye group were 4.17%, 6.25%, and 10.42% at 1 month, 3 months, and 6 months after treatment; and the recurrence rates of the normal saline group were: 18.75%, 25.00%, and 35.42%. The difference in recurrence rate was statistically significant(P<0.05)between these two groups.Conclusion Kangfuxin solution has a good effect in the treatment of hormone-dependent dermatitis and can reduce the recurrence of the disease.

Key words: hormone-dependent dermatitis, Kangfuxin solution, physiological saline

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