芳香疗法在癌症患者化疗相关恶心呕吐中的应用进展

doi:10.3969/j.issn.1674-490X.2024.01.010

摘要/Abstract

摘要： 对芳香疗法在癌症患者化疗相关恶心呕吐(chemotherapy related nausea and vomiting,CINV)中的应用进行综述,详细介绍CINV的概念、分类、发生机制、防治措施,芳香疗法的定义、起源与发展、操作方法、作用机制、在现代临床的应用现状以及在癌症患者CINV中的应用现状,提出现存问题和后续研究方向,为该方法在癌症患者CINV中的相关护理提供参考依据。

关键词: 化疗相关恶心呕吐, 芳香疗法, 癌症

Abstract: The applications of aromatherapy in chemotherapy related nausea and vomiting(CINV)in cancer patients were summarized in order to provide a detailed introduction to the concept, classification, pathogenesis, and prevention and treatment measures of chemotherapy related nausea and vomiting; The definition, origin and development, operation method, mechanism of action, application status in modern clinic and application status in CINV of cancer patients of aromatherapy were introduced, and the existing problems and follow-up research directions were discussed to provide reference for the related care of this method in CINV of cancer patients.

Key words: chemotherapy related nausea and vomiting, aromatherapy, cancer

中图分类号:

R473.73

孟悦,孟佳,王玥,刘小会,李延红,陈荟婧. 芳香疗法在癌症患者化疗相关恶心呕吐中的应用进展[J]. 医学研究与教育, 2024, 41(1): 71-75.

参考文献

[1] 国家癌症中心发布最新一期全国癌症统计数据[J].上海护理, 2022, 22(4): 72.
[2] XIA C, DONG X, LI H, et al. Cancer statistics in China and United States, 2022: profiles, trends, and determinants[J]. Chin Med J(Engl), 2022, 135(5): 584-590. DOI: 10.1097/cm9.0000000000002108.
[3] SMIT T, KOTZE I, DU PLESSIS J. The incidence of nausea in the absence of vomiting in patients receiving intravenous chemotherapy[J]. Ann Palliat Med, 2021, 10(3): 2679-2686. DOI: 10.21037/apm-19-453.
[4] 陆丹,张伟玲,龙凤丹,等.化疗后恶心呕吐发生率的调查[J].当代护士(下旬刊), 2021, 28(7):35-36. DOI: 10.19793/j.cnki.1006-6411.2021.21.012.
[5] 上海市抗癌协会癌症康复与姑息专业委员会.化疗所致恶心呕吐全程管理上海专家共识(2018年版)[J].中国癌症杂志, 2018, 28(12): 946-953. DOI: 10.19401/j.cnki.1007-3639.2018.12.011.
[6] 程梦慧,卢咏梅,肖文莉,等.柠檬生姜香薰吸入对乳腺癌患者化疗相关性恶心呕吐的临床疗效观察[J].实用临床医药杂志, 2018, 22(14):97-100. DOI: 10.7619/jcmp.201814028.
[7] 孙海燕,马韦韦,高学群,等.芳香疗法联合鲜姜片在结肠癌术后患者化疗相关性恶心呕吐中的应用[J].临床普外科电子杂志, 2022, 10(3):130-133, 173. DOI: 10.3969/j.issn.2095-5308.2022.03.034.
[8] 张旭莲.芳香疗法在癌症患者症状管理中的应用进展[J].上海医药, 2022, 43(2): 35-38, 46.
[9] 方婷,马红梅,王念,等.芳香疗法应用研究进展[J]. 护理研究, 2019, 33(23):4093-4095. DOI: 10.12102/j.issn.1009-6493.2019.23.020.
[10] KEYHANMEHR A S, KOLOURI S, HEYDARIRAD G, et al. Aromatherapy for the management of cancer complications: a narrative review[J]. Complement Ther Clin Pract, 2018, 31: 175-180. DOI: 10.1016/j.ctcp.2018.02.009.
[11] 杨凡,刘莲,曹邦伟.化疗相关恶心呕吐的发生机制及治疗药物的研究进展[J].中国医院用药评价与分析, 2017, 17(8): 1013-1016.
[12] 程颖,柳菁菁.《中国肿瘤药物治疗相关恶心呕吐防治专家共识(2022年版)》解读[J].临床内科杂志, 2023, 40(5): 351-353. DOI: 10.3969/j.issn.1001-9057.2023.05.020.
[13] 任旭春.中医中药辅助治疗化疗引起的恶心呕吐[J]. 健康向导, 2021, 27(6):48-49. DOI: 10.3969/j.issn.1006-9038.2021.06.031.
[14] 郭芷君,徐峰.化学治疗所致恶心呕吐分类与药物治疗的研究进展[J].中国药业, 2020, 29(22):1-6. DOI: 10.3969/j.issn.1006-4931.2020.22.001.
[15] 肖彩芝,王维,夏冬琴,等.化疗所致恶心呕吐中西医诊治专家共识[J].中国医院用药评价与分析, 2023, 23(12): 1409-1415, 1421. DOI: 10.14009/j.issn.1672-2124.2023.12.001.
[16] 倪宏,刘玉,覃惠英,等.化疗相关性恶心呕吐的非药物干预研究进展[J].护理研究, 2020, 34(20): 3674-3677. DOI: 10.12102/j.issn.1009-6493.2020.20.021.
[17] 魏宇梅,洪岩,费夷敏,等.芳香疗法概述[J].中医学报, 2015, 30(1): 140-142. DOI: 10.16368/j.issn.1674-8999.2015.01.047.
[18] 王鹏程,孟爱凤,智晓旭,等.芳香疗法预防肿瘤患者化疗后恶心及呕吐的系统评价[J].解放军护理杂志, 2020, 37(4):6-10. DOI: 10.3969/j.issn.1008-9993.2020.04.002.
[19] 宋宁,周欣,弓宝,等.中医芳香疗法历史溯源及现代临床应用初探[J].香料香精化妆品, 2021(6): 94-98. DOI: 10.3969/j.issn.1000-4475.2021.06.020.
[20] 李芷悦,李峰,张煜,等.中西医“芳香疗法”发展路径的比较研究[J].中国医药导报, 2017, 14(28):93-96. DOI: 10.3969/j.issn.1004-6852.2015.03.019.
[21] 赵倩,章雅儒,李彦强,等.芳香精油疗法对失眠症病人睡眠质量的影响[J].循证护理, 2023, 9(14): 2611-2615.
[22] 张嘉钰,童海涛,章德林.浅探芳香疗法防治抑郁症[J]. 光明中医, 2022, 37(14):2524-2527. DOI: 10.3969/j.issn.1003-8914.2022.14.019.
[23] ZHANG P J, LIAO X, YUAN Q, et al. Effect of aromatherapy on postoperative pain relief: a systematic review and meta-analysis of randomized controlled trials[J]. Eur J Integr Med, 2023, 62: 102289. DOI: 10.1016/j.eujim.2023.102289.
[24] 尹婷,韩侨,赵春善.芳香疗法对初产妇产痛及产程时间影响的Meta分析[J].中国妇幼保健, 2020, 35(20): 3906-3909. DOI: 10.19829/j.zgfybj.issn.1001-4411.2020.20.062.
[25] RAMBOD M, PASYAR N, KARIMIAN Z, et al. The effect of lemon inhalation aromatherapy on pain, nausea, as well as vomiting and neurovascular assessment in patients for lower extremity fracture surgery: a randomized trial[J]. BMC Complement Med Ther, 2023, 23(1): 208. DOI: 10.1186/s12906-023-04047-z.
[26] 刘雅洁,林瑶,赵百孝.芳香疗法治疗阿尔茨海默病的研究进展[J].中华中医药杂志, 2022, 37(7): 3982-3985. DOI: 10.3969/j.issn.1004-745X.2020.01.050.
[27] 彭晓婕,江振强,陈赞美,等.茶树精油在失禁性皮炎重症患者护理中的应用[J].中国医药科学, 2020, 10(9): 104-106. DOI: 10.3969/j.issn.2095-0616.2020.09.031.
[28] 张煜,李婧昳,卓嘎,等.香药在变应性鼻炎诊疗中的应用[J].中国医药导报, 2018, 15(10): 99-101.
[29] 王维维,刘赞,蔡小霞.芳香疗法对躯体疾病患者疲乏干预作用的研究进展[J].职业与健康, 2020, 36(24): 3451-3456.
[30] 王旭梅,王莉,郭欣,等.中医芳香疗法缓解神经母细胞瘤患儿化疗期间预期性恶心呕吐的效果分析[J].护理研究, 2021, 35(17): 3119-3124. DOI: 10.12102/j.issn.1009-6493.2021.17.021.
[31] 樊玮炜,高莉,吴忠梅.果皮面罩吸入对顺铂化疗患者恶心呕吐的影响[J].当代护士(上旬刊), 2021,28(10): 86-88. DOI: 10.19791/j.cnki.1006-6411.2021.28.031.
[32] 丁静,吴祥凤,蔡佩青,等.香佩疗法对食管癌化疗相关性恶心呕吐的影响[J]. 当代护士(中旬刊), 2021, 28(11):54-57. DOI: 10.19792/j.cnki.1006-6411.2021.32.019.
[33] 翟田田.吸入性芳香疗法缓解顺铂化疗相关性恶心呕吐的临床疗效研究[D].兰州:兰州大学,2021:1-58.
[34] 郝秀乔,冯蕾,宋博宁,等.芳香疗法缓解淋巴瘤患者化疗后恶心呕吐的护理体会[J].中外医学研究, 2020, 18(16): 108-109. DOI: 10.14033/j.cnki.cfmr.2020.16.043.
[35] 杨敏敏.隔姜灸联合芳香疗法对宫颈癌患者化疗所致恶心呕吐的临床观察[D].兰州:甘肃中医药大学,2023:1-53.
[36] 宾湘赣.芳香药囊治疗恶性血液疾病化疗相关相关性恶心、呕吐临床观察[D].广州:广州中医药大学,2020:1-32.
[37] 侯云霞,强万敏,于立娟,等.芳香按摩疗法对晚期肺癌患者化疗相关性恶心呕吐干预效果的研究[J].中国实用护理杂志, 2018, 34(7): 495-501. DOI: 10.3760/cma.j.issn.1672-7088.2018.07.004.