医学研究与教育 ›› 2014, Vol. 31 ›› Issue (5): 13-15.

• 临床研究 • 上一篇    下一篇

乙肝病毒既往感染者血清 HBV DNA 检测

马士恒,李明   

  1. 河北大学附属医院感染性疾病科,河北 保定 071000
  • 收稿日期:2015-01-16 修回日期:2015-01-16 出版日期:2014-10-25 发布日期:2014-10-25
  • 作者简介:马士恒(1968— ),男,河北博野人,主任医师,硕士,主要从事感染性疾病的诊治及教学工作。E-mail: mashiheng@126.com

Detection of serum HBV DNA in past infection people of Hepatitis B virus

MA Shiheng, LI Ming   

  1. Infectious Diseases Department, Affiliated Hospital of Hebei Univercity, Baoding 071000, China
  • Received:2015-01-16 Revised:2015-01-16 Online:2014-10-25 Published:2014-10-25

摘要: 目的 研究 HBV 既往感染者血清中 HBV DNA。方法从门诊健康体检者中筛选 HBV 既往感染者,应用 PCR 方法检测血清 HBV DNA。结果 HBV 既往感染者血清 HBV DNA 阳性率为 3.39%,但较 HBV 携带者低,χ2=146.109,P=0.000。HBV 既往感染者血清 HBV DNA 阳性者血清 HBV DNA 对数均值为 3.93±0.90,明显低于 HBV 携带者,F=14.846,P=0.000。结论 部分 HBV 既往感染者体内仍有 HBV 低水平复制,其意义有待研究。

关键词: 乙肝病毒, 既往感染, HBV DNA, 乙肝血清学标志物

Abstract: Objective To detect the serum HBV DNA in people infected previously. Methods Past HBV infection people were screened from physical examination persions in Out-patient department. The serum HBV DNA were detected by PCR.Results The positive rate of the serum HBV DNA in past HBV infection people was 3.39%. It was lower than in HBV carriers, χ2= 146.109, P=0.000. Logarithmic Mean of the serum HBV DNA in HBV DNA positive people of the past HBV infection was 3.93±0.90. It was lower than in HBV carriers, F=14.846, P=0.000. Conclusion There are low level HBV reproductions in some past HBV infection people. Its significance needs to study further.

Key words: Hepatitis B virus, Past infection, HBV DNA, Serum HBV markers

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