干细胞治疗心脏疾患研究进展

医学研究与教育 ›› 2014, Vol. 31 ›› Issue (5): 55-58.

干细胞治疗心脏疾患研究进展

瞿海龙1，麻月云²，边剑飞¹

1. 河北大学附属医院急诊科，河北保定 071000；2.保定市妇幼保健院，河北保定 071000

收稿日期:2015-01-16 修回日期:2015-01-16 出版日期:2014-10-25 发布日期:2014-10-25
作者简介:瞿海龙（1976—），男，河北涞水人，副主任医师，硕士，主要从事急救医学。E-mail: hailongju1976@sohu.com

Advances on stem cells in the treatment of cardiac diseases

JU Hailong¹, MA Yueyun², BIAN Jianfei¹

1. Emergency Department, Affiliated Hospital of Hebei University, Baoding 071000, China; 2. Maternal and Child Care Service Centre of Baoding, Baoding 071000, China

Received:2015-01-16 Revised:2015-01-16 Online:2014-10-25 Published:2014-10-25

摘要/Abstract

摘要： 随着再生医学研究的深入，干细胞移植已用于临床实验。目前成骨骼肌细胞、骨髓源性干细胞、间充质干细胞和心肌固有干细胞已应用于心肌再生治疗。其中 C-kit 阳性心肌干细胞移植，不仅对收缩性心力衰竭有明确疗效，而且从长远来看，无明显不良事件发生。现就与心肌再生相关细胞作一综述，阐述何类细胞更适于心脏疾患的治疗。

关键词: 再生医学, 干细胞, 心肌梗死

Abstract: Various researches on regenerative medicine were carried out experimentally, and selected modalities have been introduced to the clinical arena. So far skeletal myoblasts, bone marrow-derived cells, mesenchymal stromal cells, and resident cardiac cells have been applied for therapeutic myocardial regeneration. Among them, autologous transplantation of c-kit-positive cardiac stem cells in congestive heart failure patients resulted in an outstanding outcome, with long-lasting beneficial effects without major adverse events. By reviewing these clinical trials, an endeavor was made to seek for an ideal cellular therapy for cardiovascular diseases.

Key words: regenerative medicine, stem cells, myocardical infarction

中图分类号:

R542.2

瞿海龙，麻月云，边剑飞. 干细胞治疗心脏疾患研究进展[J]. 医学研究与教育, 2014, 31(5): 55-58.

JU Hailong, MA Yueyun, BIAN Jianfei. Advances on stem cells in the treatment of cardiac diseases[J]. Medical Reserch and Education, 2014, 31(5): 55-58.

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