关键词: 间苯三酚, 青少年, 无痛人工流产术

Abstract: Objective To investigate the effect of preoperative application of phloroglucin in adolescent painless induced abortion. Methods Between January, 2011, and May, 2014, 52 adolescent pregnant women requiring induced abortion in our out-patient department, aged 14 to 19 years old, were randomly divided into two groups. 27 patients in observation group and 25 in control group. Before the start of the operation for 10 min, the patients in the observation group were given 80 mg phloroglucin intravenously, then 1.50-2.50 mg/kg propofol intravenuously until the patients lost consciousness, and then received the induced abortion. Patients in control group were only treated with propofol with the same dose for painless induced abortion. Observation index included uterus flabby degree, operation time, analgesic effect and the occurrence of artificial abortion syndrome. Results The effective rate of analgesia was 96.29% in the observation group, and 88.00% in control group. There were significant differences between two groups ( P<0.05). There was also significant difference between two groups in the uterus flabby degree, operation time and the occurrence of induced abortion syndrome control group ( P<0.05). Patients in the observation group had no complications, while one patient in the control group appeared complication of uterine perforation because of tight Uterus. Conclusion The application of phloroglucin intravenously in adolescent painless induced abortion, can significantly enhance the analgesic effect, effectively improve the uterus flabby degree, shorten the operation time, reduce the incidence of induced abortion syndrome. Therefore it can be used to reduce the occurrence of complications, which is worthy to be distributed in clinical practice.

Key words: phloroglucin, adolescent, painless induced abortion