医学研究与教育 ›› 2014, Vol. 31 ›› Issue (6): 31-35.

• 临床研究 • 上一篇    下一篇

社区综合管理联合帕罗西汀在恶性消化道肿瘤患者抑郁、焦虑状态的应用

苏雷1,胡玲1,容明钦2,张建军1   

  1. 1. 河北大学附属医院,河北 保定 071000;2. 海军总医院,北京 100000
  • 出版日期:2014-12-25 发布日期:2014-12-25
  • 通讯作者: 胡玲(1980—),女,河北保定人,主治医师,硕士,主要从事肿瘤科临床及基础研究。E-mail: 57461548@qq.com
  • 作者简介:苏雷(1981—),男,河北保定人,主治医师,硕士,主要从事肿瘤科临床及基础研究。E-mail: 50099552@qq.com
  • 基金资助:
    保定市哲学社会科学规划研究项目(20140417)

Application of community comprehensive management combined with Paroxetine in relieving depression and anxiety of patients with digestive malignancy

SU Lei1, HU Ling1, RONG Mingqin2, ZHANG Jianjun1   

  1. 1. Affiliated Hospital of Hebei University, Baoding 071000, China; 2. PLA Navy General Hospital, Beijing 100000, China
  • Online:2014-12-25 Published:2014-12-25

摘要: 目的 探讨社区综合管理联合帕罗西汀治疗在恶性消化道肿瘤患者抑郁、焦虑状态中的应用。方法 通过对中国中等城市社区卫生中心辖区内,2011 年 2 月至 2014 年 2 月已确诊恶性消化道肿瘤且存在抑郁、焦虑状态患者 89 例为研究对象,对入组患者采用口服帕罗西汀药物治疗联合社区综合防治管理进行心理干预。分别对治疗前后进行 SCL-90、SAS、SDS、FACT-G 测评,并进行统计学分析。结果 对社区消化道肿瘤患者社区综合管理联合帕罗西汀前 SCL-90 评分显示, 确实存在着抑郁及焦虑状态。患者经社区综合管理联合帕罗西汀前后 SCL-90 评分比较,提示社区综合管理联合帕罗西汀对 SCL-90 各项评分均有改善,具有统计学意义(P<0.05)。应用社区综合管理联合帕罗西汀治疗前及治疗后的恶性消化道肿瘤患者抑郁及焦虑评分对比:恶性消化道肿瘤患者应用联合治疗后 SAS、SDS、FACT-G 评分比治疗前显著下降(P<0.05)。结论 社区综合管理联合帕罗西汀在消化道肿瘤患者抑郁、焦虑状态治疗中有积极作用,能显著提高恶性消化 道肿瘤患者生活质量。

关键词: 社区综合管理, 帕罗西汀, 消化道肿瘤, 抑郁, 焦虑

Abstract: Objective To explore the treating effects of community comprehensive management combined with Paroxetine in relieving depression and anxiety of patients with digestive malignancy. Methords 89 digestive malignancy patients with depression and anxiety were researched in the Community health center areas of medium-sized cities, which was treated with Paroxetine combined with community comprehensive management. The SCL-90 SAS SDS and FACT-G were analyzed by statistical method before and after treatment between 2011.2 and 2014.2. Results SCL-90 scores indicated that patients in the survey community had depression, anxiety before the treatment. And the SCL-90 scores were improved after the treatment, there was statistically differences (P<0.05). Comparing SAS SDS FACT-G scores for estimating depression and anxiety degrees of patients, they were decreased obviously after the treatment (P<0.05). Conclusion Community comprehensive management with Paroxetine is an effective treatment to relieve depression and anxiety status, and can improve the life quality of digestive malignancy patients.

Key words: community comprehensive management, Paroxetine, digestive malignancy, depression, anxiety

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