慢性肾脏病骨质疏松发病机制的研究进展

doi:10.3969/j.issn.1674-490X.2019.04.003

摘要/Abstract

摘要： 骨质疏松(osteoporosis, OP)是慢性肾脏病(chronic kidney disease, CKD)患者骨代谢紊乱常见的并发症之一,是导致CKD患者脆性骨折最主要的骨代谢性疾病,增加患者的致残率和病死率。因此,就CKD骨质疏松的发病机制进行综述,以期为CKD患者骨质疏松症的防治提供思路。

关键词: 慢性肾脏病(CKD), 骨代谢异常, 骨密度(BMD), 骨质疏松

Abstract: Objective Osteoporosis(OP)is one of the common complications of bone metabolic disorders in patients with chronic kidney disease(CKD), which is the most important bone metabolic disorder leading to fragile fracture in CKD patients, increasing the disability rate and mortality rate. Therefore, the pathogenesis of CKD osteoporosis is reviewed in order to provide ideas for the prevention and treatment of osteoporosis in CKD patients.

Key words: chronic kidney disease(CKD), abnormal bone metabolism, bone mineral density(BMD), osteoporosis

中图分类号:

左彦波,贾娟,王红杰. 慢性肾脏病骨质疏松发病机制的研究进展[J]. 医学研究与教育, 2019, 36(4): 10-18.

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