儿童热性惊厥发作的昼夜分布特点及相关影响因素

doi:10.3969/j.issn.1674-490X.2022.02.004

医学研究与教育 ›› 2022, Vol. 39 ›› Issue (2): 24-28.DOI: 10.3969/j.issn.1674-490X.2022.02.004

儿童热性惊厥发作的昼夜分布特点及相关影响因素

侯婷,钟小毅,魏继红

河北大学附属医院儿科, 河北保定 071000

收稿日期:2021-10-11 出版日期:2022-04-25 发布日期:2022-04-25
通讯作者: 魏继红(1982—),女,湖北武汉人,副主任医师,硕士,硕士生导师,主要从事儿童重症疾病的救治。E-mail: 15176257362@139.com
作者简介:侯婷(1993—),女,安徽宿州人,住院医师,在读硕士,主要从事儿童神经系统疾病的研究。 E-mail: 1846605474@qq.com

Diurnal distribution characteristics and related influencing factors of febrile seizures in children

HOU Ting,ZHONG Xiaoyi,WEI Jihong

Department of Pediatrics, Affiliated Hospital of Hebei University, Baoding 071000, China

Received:2021-10-11 Online:2022-04-25 Published:2022-04-25

摘要/Abstract

摘要： 目的探讨儿童热性惊厥发作的昼夜分布特点及相关影响因素。方法回顾性分析河北大学附属医院儿科2014年1月至2019年12月收住院的443例热性惊厥患儿发作次数的昼夜分布特点,并分析性别(男/女)、初发年龄(≤3岁/>3岁)、胎龄(早产/足月)及出生方式(剖宫产/顺产)对热性惊厥发作昼夜分布的影响作用。结果热性惊厥发作次数的昼夜分布差异有统计学意义(χ²=5.411,P=0.020);单因素分析结果显示,不同性别、初发年龄、胎龄的患儿发作的昼夜分布差异均有统计学意义(均P<0.05);Logistic回归分析发现,初发年龄、胎龄是儿童热性惊厥发作昼夜分布的影响因素,差异均有统计学意义(均P<0.05)。结论儿童热性惊厥发作的昼夜分布有一定特点,且受初发年龄、胎龄的影响。

关键词: 儿童, 热性惊厥, 昼夜分布, 发作次数

Abstract: Objective To explore the diurnal distribution characteristics and related factors of the number of febrile convulsions in children. Methods The diurnal distribution characteristics of 443 children with febrile convulsion hospitalized in the Department of Pediatrics of Affiliated Hospital of Hebei University from January 2014 to December 2019 were analyzed retrospectively. The effects of gender(male/female), age at onset(≤3 years old/>3 years old), gestational age(preterm birth/term birth)and birth mode(caesarean delivery/natural delivery)on the day-night distribution of febrile seizures were analyzed. Results The diurnal distribution of the number of seizures was different(χ²=5.411,P=0.020), the results of univariate analysis showed that there were differences in the day and night distribution of seizures in children with different genders, age at first onset, and gestational age(all P<0.05). Logistic regression analysis showed that age at onset and gestational age the influencing factors of the diurnal distribution of febrile seizures in children, and the differences were statistically significant(all P<0.05).Conclusion The diurnal distribution of the number of febrile convulsions in children has certain characteristics, which is affected by age at onset and gestational age.

Key words: children, febrile convulsion, diurnal distribution, number of seizures

中图分类号:

侯婷,钟小毅,魏继红. 儿童热性惊厥发作的昼夜分布特点及相关影响因素[J]. 医学研究与教育, 2022, 39(2): 24-28.

HOU Ting,ZHONG Xiaoyi,WEI Jihong. Diurnal distribution characteristics and related influencing factors of febrile seizures in children[J]. Journal of Hebei Medical College for Continuing Education, 2022, 39(2): 24-28.

参考文献

[1] SMITH D K, SADLER K P, BENEDUM M. Febrile seizures: risks, evaluation, and prognosis[J]. Am Fam Physician, 2019, 99(7): 445-450.
[2] MEWASINGH L D, CHIN R F M, SCOTT R C. Current understanding of febrile seizures and their long-term outcomes[J]. Dev Med Child Neurol, 2020, 62(11): 1245-1249. DOI: 10.1111/dmcn.14642.
[3] SAWIRES R, BUTTERY J, FAHEY M. A review of febrile seizures: recent advances in understanding of febrile seizure pathophysiology and commonly implicated viral triggers[J]. Front Pediatr, 2022, 9: 801321. DOI: 10.3389/fped.2021.801321.
[4] 刘素云,陈思,张露娇,等.儿童热性惊厥临床特征分析[J].医学信息, 2021, 34(8): 116-118. DOI: 10.3969/j.issn.1006-1959.2021.08.030.
[5] 李爱月,张巧丽,赵燕芳,等.616例小儿热性惊厥首次发作的临床特点及危险因素分析[J].中国小儿急救医学, 2020, 27(4): 298-301. DOI: 10.3760/cma.j.issn.1673-4912.2020.04.013.
[6] 温清芬,王芳,林亚芬.298例小儿首次热性惊厥发作的临床特征及其影响因素分析[J].中国妇幼保健, 2017, 32(9): 1933-1936. DOI: 10.7620/zgfybj.j.issn.1001-4411.2017.09.38.
[7] LI B, WU Y J, HE Q J, et al. The effect of complicated febrile convulsion on hippocampal function and its antiepileptic treatment significance[J]. Transl Pediatr, 2021, 10(2): 394-405. DOI: 10.21037/tp-20-458.
[8] 娄季鹤,赵孝开,李树仁,等.烧伤并发严重阵发性交感神经过度兴奋综合征的早期诊断与处理[J].中华烧伤杂志, 2019, 35(8): 599-603. DOI: 10.3760/cma.j.issn.1009-2587.2019.08.008.
[9] RISSARDO J P, CAPRARA A L F, SILVEIRA J O F. Generalized convulsive status epilepticus secondary to jarisch-herxheimer reaction in neurosyphilis: a case report and literature review[J]. Neurologist, 2019, 24(1): 29-32. DOI: 10.1097/NRL.0000000000000219.
[10] LEUNG A K, HON K L, LEUNG T N. Febrile seizures: an overview[J]. Drugs Context, 2018, 7: 212536. DOI: 10.7573/dic.212536.
[11] 马小龙,施森,马金海,等.462例儿童热性惊厥临床特征分析[J].宁夏医科大学学报, 2021, 43(10): 1013-1016. DOI: 10.16050/j.cnki.issn1674-6309.2021.10.006.
[12] 闵燕华,戚锋锋,金薇.428例儿童热性惊厥临床特征及复发因素分析[J]. 中国妇幼保健, 2019, 34(18): 4226-4228. DOI: 10.7620/zgfybj.j.issn.1001-4411.2019.18.38.
[13] 武小玉,娄涛,李冲,等.FC患儿发病年龄、发作次数及脑电图与预后的关系[J].中国现代医学杂志, 2008, 18(15): 2208-2210. DOI: 10.3969/j.issn.1005-8982.2008.15.028.
[14] 范嘉玲.小儿热性惊厥发作的昼夜节律和季节节律的初步探讨[D].广州:南方医科大学, 2020: 29-31. DOI: 10.27003/d.cnki.gojyu.2020.000798.
[15] 袁嘉嵘,李楠.早产儿与足月儿1岁内快速生长和生长发育状况比较[J].中国妇幼保健, 2021, 36(2): 338-340. DOI: 10.19829/j.zgfybj.issn.1001-4411.2021.02.030.
[16] 朱庆庆,花静,杨青.上海市早产儿与足月儿3~6岁睡眠模式比较分析[J].中国儿童保健杂志, 2020, 28(11): 1201-1204.

儿童热性惊厥发作的昼夜分布特点及相关影响因素

Diurnal distribution characteristics and related influencing factors of febrile seizures in children

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 13

编辑推荐

Metrics

本文评价

[1]	王密,陈菁菁,刘芳,张艳,齐景. 中国学龄前儿童乳牙龋病影响因素的Meta分析[J]. 医学研究与教育, 2022, 39(2): 41-47.
[2]	王霜霜,王鑫鑫,郭玉芳,徐月清,薛桂花. 癌症儿童安宁疗护影响因素及对策研究进展[J]. 医学研究与教育, 2019, 36(5): 45-51.
[3]	霍丽娇,王琨,柏金秀,马腾腾,魏继红. 肾炎康复片联合激素治疗儿童紫癜性肾炎的临床疗效及安全性分析[J]. 医学研究与教育, 2019, 36(2): 28-32.
[4]	靳晓明,杨尧,孙世辉,张帅. 基于数据挖掘中医治疗儿童过敏性紫癜辨证和用药规律[J]. 医学研究与教育, 2018, 35(3): 39-43.
[5]	方玉婷，姜玲，史天陆，孙言才. 孟鲁司特钠佐治儿童肺炎支原体肺炎的疗效与安全性 meta 分析[J]. 医学研究与教育, 2014, 31(5): 29-33.
[6]	徐海霞,徐利平,卢红利,韩宁林. 连续护理干预对过敏性紫癜患儿的影响[J]. 医学研究与教育, 2014, 31(2): 80-82,86.
[7]	王婷婷,吕新,李榕,邵红. 儿童少年卫生学与儿童保健学课程合并的优势[J]. 医学研究与教育, 2014, 31(1): 101-104.
[8]	张进国,徐晶,于健,张保宗,唐术玲. 不同干预措施对缺碘地区8~10岁儿童尿碘水平的影响[J]. 医学研究与教育, 2013, 30(5): 57-61.
[9]	刘树芳,杨洋,杨洋. 保定市城乡结合部某幼儿园儿童食谱定性分析[J]. 医学研究与教育, 2013, 30(4): 54-59.
[10]	张进国,王彦辉,孙晓丽,李铁库,刘建华,付兰娥. 2012年易县8~10岁儿童尿碘水平[J]. 医学研究与教育, 2013, 30(4): 50-53.
[11]	张艳丽. 儿童预防接种前常规体检的必要性[J]. 医学研究与教育, 2013, 30(3): 37-39.
[12]	李燕广,张进国,张保宗,唐术玲,刘建华. 河北省易县儿童不同时期甲状腺肿流行特征及干预效果评价[J]. 医学研究与教育, 2013, 30(3): 50-54.
[13]	张进国,孙晓丽,李铁库,李燕广,王斐然,付兰娥. 碘缺乏病综合干预对学龄儿童甲状腺肿大率的影响[J]. 医学研究与教育, 2012, 29(6): 35-38.