Abstract: Objective To investigate the related risk factors of myocardial enzyme changes in patients with cerebral hemorrhage. Methods 125 patients with acute cerebral hemorrhage, according to the amount of bleeding, the bleeding site and Glasgow score were studied retrospectively, all patients were divided into corresponding groups, compared with 50 health physical examination cases, the changes of myocardial enzyme in acute stage were observed. Meanwhile myocardial enzyme changes were monitored to acquaint the enzyme change trend. Results Compared with healthy control group, the patients‘amount of bleeding in the experimental group was less than 20 mL, Glasgow score was more than 12, which had not a signiifcant difference in myocardial enzyme (P>0.05), the patient’s amount of bleeding was more than 20 mL, Glasgow score less than 12 , which had a significant difference in myocardial enzyme (P<0.05), Myocardial enzyme changes were associated with the bleeding site. Thalamic hemorrhage had the most significant changes in myocardial enzymes. Myocardial enzyme reached peak at 72 hours in the patients with cerebral hemorrhage,14 days returned to normal level. Conclusion The changes of myocardial enzyme in patients with cerebral hemorrhage is closely related with the amount of bleeding, the bleeding site and the severity of the disease, which can be used as an effective indictor to monitor disease progression and prognosis.

Key words: cerebral hemorrhage, myocardial enzyme, Glasgow score