doi:10.3969/j.issn.1674-490X.2018.06.004

Abstract

Abstract: Objective To observe the effects of magnetic field intervention on the distribution of blood vessels in the scar after peripheral nerve injury in rats. Methods 160 SD rats were divided into 4 groups at random, 40 rats in each group. The experimental rats were made sciatic nerve injury model. Low intensity, medium intensity and high intensity(0.2 mT, 0.6 mT and 1.5 mT)were given to the experimental group for magnetic field intervention with a frequency of 20 Hz and 60 min/d. The rats of the control group were raised normally without treatment. At the 8th week after operation, vascular perfusion and immunohistochemistry were performed to observe the distribution of blood vessels at the nerve scar. Results At 8 weeks after surgery, compared with the control group(P<0.01), the blood vessels in the experimental group were more evenly distributed, more abundant, higher density and more regular vascular shape. Conclusion The magnetic field can change the blood vessel distribution at the nerve scar and improve the blood supply to the nerve tissue at the injury.

Key words: magnetic field, nerve scar, sciatic nerve injury, nerve regeneration, angioarchitecture

CLC Number:

R361

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[1]	. [J]. Journal of Hebei Medical College for Continuing Education, 2021, 38(6): 36-43.
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