Advances on stem cells in the treatment of cardiac diseases

Abstract

Abstract: Various researches on regenerative medicine were carried out experimentally, and selected modalities have been introduced to the clinical arena. So far skeletal myoblasts, bone marrow-derived cells, mesenchymal stromal cells, and resident cardiac cells have been applied for therapeutic myocardial regeneration. Among them, autologous transplantation of c-kit-positive cardiac stem cells in congestive heart failure patients resulted in an outstanding outcome, with long-lasting beneficial effects without major adverse events. By reviewing these clinical trials, an endeavor was made to seek for an ideal cellular therapy for cardiovascular diseases.

Key words: regenerative medicine, stem cells, myocardical infarction

CLC Number:

R542.2

JU Hailong, MA Yueyun, BIAN Jianfei. Advances on stem cells in the treatment of cardiac diseases[J]. Medical Reserch and Education, 2014, 31(5): 55-58.

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