Abstract: Objective To investigate the blood rheology changes during hysteroscopic resection of submucous uterine fibroids and provide a theoretical basis for clinical treatment. Methods From January to December, 2014, 45 cases with submucous uterine fibroids were conducted hysteroscopic surgery in Dingxing hospital, before perfusion 10 min (T₁), perfusion 30 min (T₂), after surgery , blood rheology index level (T₃) were detected. Results All cases were successfully conducted the operation, T₃, T₂ point blood rheology index of whole blood low-cut, middle cut high cut, low-cut reduction of whole blood, blood high shear reduced, plasma viscosity, etc.,erythrocyte rigidity index, aggregation index, deformation index and maximum platelet aggregation compared with the index at T₁, the difference was statistically significant (P<0.05). T₂ point hematocrit compared with T₁ point indicator, the difference was statistically significance (P<0.05). T₃ point high shear whole blood, plasma viscosity, etc., hematocrit, erythrocyte rigidity index, maximum platelet aggregation compared with T₂ each index point, the difference was statistically significant (P<0.05). Conclusion Perioperative blood rheology indicators for monitoring is necessary when longer operative time, more fluid absorption to reduce blood viscosity in patients with uterine fibroids after operation and protect red blood cells , reduce cardiovascular events and deep venous thrombosis.

Key words: submucosal uterine fibroids, blood rheology, hysteroscopic surgery