Abstract: Objective The reliability and necessity of the drainage technique were discussed by comparing the application of drainage technique in the clinical application of acellular matrix material biological mesh. Methods Forty-three patients with inguinal hernia were divided into two groups, all of whom were treated with Biodesign Surgisis(SIS)biological mesh for inguinal hernia repair. Twenty-one patients in the experimental group were treated with drainage technology, while 22 patients in the control group were not treated with drainage technology. The postoperative indicators and complications such as seroma, postoperative infection and chronic pain in the two groups were statistically analyzed. Results After statistical observation and comparison, there was a significant difference in postoperative seroma between patients with and without drainage devices(P<0.05). There was no significant difference in postoperative indicators, postoperative infection, postoperative chronic pain, postoperative foreign body sensation, postoperative recurrence, etc.(P>0.05). Conclusion The application of drainage device can reduce the occurrence of adverse events of seroma after the repair of inguinal hernia with acellular matrix material biological mesh.

Key words: biological patch, seroma, tension-free herniorrhaphy, the drainage device