doi:10.3969/j.issn.1674-490X.2021.03.001

Abstract

Abstract: Umbilical cord blood has gradually become an important source of stem cells in allogeneic stem cell transplantation.Although the post-transplantation infective fatality rate is higher, the survival rate of cord blood transplantation is comparable to other types of stem cell transplantation due to the advantages of easy access and lower incidence of GVHD(graft-versus-host diseases, GVHD).The improvement of cord blood transplantation technology has also brought better curative effect to the patients. The clinical application of umbilical cord blood provides a new method for the treatment of many refractory diseases.This article reviews the improvement of cord blood transplantation in recent years, the selection of cord blood for transplantation and the application of umbilical cord blood in other related diseases.

Key words: umbilical cord blood, stem cell transplantation, graft-versus-host diseases, cell therapy

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References

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