医学研究与教育 ›› 2013, Vol. 30 ›› Issue (4): 72-74,88.DOI: 10.3969/j.issn.1674-490X.2013.04.018

• 综述 • 上一篇    下一篇

急性脑损伤患者肠道屏障功能检测研究进展

王惠凌1,李同凯1,李强1,陈玉敏2   

  1. 1.河北大学附属医院神经内科,河北 保定,071000
    2.河北大学基础医学院,河北 保定,071000
  • 出版日期:2013-08-25 发布日期:2013-08-25
  • 基金资助:
    保定市科学技术研究与发展计划项目

Advance on intestinal mucosal barrier in patients with acute cerebral insult

WANG Huiling1,LI Tongkai1,LI Qiang1,CHEN Yumin2   

  • Online:2013-08-25 Published:2013-08-25

摘要: 近年来研究表明,机体发生急性脑损伤后可出现肠道屏障功能损伤,从而出现细菌移位及内毒素血症,引起肠源性感染,出现多脏器功能障碍及全身炎性反应综合症,严重影响患者预后,现就肠道屏障功能的不同检测指标进行阐述,意在提醒神经科医师在诊治急性脑损伤患者时注意保护患者肠道功能。

关键词: 急性脑损伤, 肠道屏障功能, 细菌移位, 内毒素血症, 多脏器功能障碍综合征, 全身炎性反应综合征

Abstract: In recent years ,some studies show that acute cerebral insult can damage gut barrier function, resulting in bacterial translocation and endotoxemia, causing multiple organ dysfunction and systemic inflammatory response syndrome, serious impact on the prognosis of patients, this paper describes the different detection index of intestinal barrier function, intending to make the neurology the physician to pay attention to the protect the intestinal function.

Key words: acute cerebral insult, intestinal mucosal barrier, Bacterial translocation, endotoxemia, multiple organ dysfunction syndrome, systemic inlfammatory response syndrome

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