医学研究与教育 ›› 2013, Vol. 30 ›› Issue (5): 35-38.DOI: 10.3969/j.issn.1674-490X.2013.05.010

• 临床研究 • 上一篇    下一篇

脑心通胶囊对急性脑梗死患者血清CRP、脂蛋白a和神经功能缺损程度评分的影响

王涛   

  1. 河北大学附属医院中西医结合科,河北 保定,071000
  • 收稿日期:2016-10-10 修回日期:2016-10-10 出版日期:2013-10-25 发布日期:2013-10-25

Effects of Naoxintong capsule on CRP, LPa and neural function defect score of ICA

WANG Tao   

  • Received:2016-10-10 Revised:2016-10-10 Online:2013-10-25 Published:2013-10-25

摘要: 目的:探讨脑心通胶囊对急性脑梗死患者 C 反应蛋白(CRP)、脂蛋白 a(LPa)及神经功能缺损程度评分的影响。方法采取随机单盲的方法,将72例住院患者分为治疗组和对照组,对照组给予西医常规治疗,治疗组在常规西医治疗的基础上加口服脑心通胶囊,2周后观察患者治疗前后CRP、LPa及神经功能缺损程度的变化。结果2周后2组CRP水平、LPa 及神经功能缺损的改善程度组内比较均具有疗效。但组间比较:CRP 水平的变化,治疗组3.09±1.02,对照组6.21±1.33,治疗组优于对照组(P<0.01);LPa的变化,治疗组302.15±140.11,对照组574.55±120.32,治疗组优于对照组(P<0.01);神经功能缺损评分方面,治疗组为6.21±2.11,对照组为9.86±3.93,治疗组优于对照组(P<0.01)。结论脑心通胶囊对于降低急性脑梗死患者CRP水平、LPa值及改善神经功能缺损方面均具有良好的疗效,值得临床推广。

关键词: 脑心通胶囊, 急性脑梗死, C反应蛋白, 脂蛋白a, 神经功能缺损程度评分

Abstract: Objective To observe the effects of Naoxintong capsule on CRP, LPa and neural function defect score of ICA. Methods 72 patients selected randomly in the Afifliated Hospital of Hebei University were divided into treatment group and control group. The treatment group was treated with Naoxintong capsule on the basis of modern medicine and the control group was treated with modern medicine. The changes of CRP, LPa and neural function defect score were observed. Results The results were both effective in the two groups in the matters of CRP, LPa and neural function defect score. And there was a significant difference between the two groups. The treating effects of the treatment group were better than that of the control group about CRP, LPa and neural function defect score(P<0.01). Conclusion The effects were signiifcant to decrease CRP and LPa and improve neurological function defect by using Naoxintong capsule, which was worthy of applying in clinical practices.

Key words: Naoxintong capsule, ICA, CRP, LPa, neural function defect score

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