迭代重建算法在肺动脉CTA 低剂量扫描中的应用研究

doi:10.3969/j.issn.1674-490X.2015.03.004

医学研究与教育 ›› 2015, Vol. 32 ›› Issue (3): 16-21.DOI: 10.3969/j.issn.1674-490X.2015.03.004

迭代重建算法在肺动脉CTA 低剂量扫描中的应用研究

赵永霞¹，²，常津³ ，左紫薇²，张畅达²，张天乐²，孟博⁴，李丹⁴，张琳琳⁴，朱长月⁴，李盛蓝⁴

1. 天津大学精密仪器与光电子工程学院，天津 300000；2. 河北大学附属医院，河北保定 071000；3. 天津大学，天津300000；4. 河北大学临床医学院，河北保定 071000

出版日期:2015-06-25 发布日期:2015-06-25
通讯作者: 常津（1963—），男，河北石家庄人，教授，博士，博士生导师，主要从事生物医学工程研究。E-mail: jinchang@tju.edu.cn
作者简介:赵永霞（1974—），男，河北石家庄人，副主任技师，硕士，硕士生导师，主要从事医学影像成像参数的优化研究。
基金资助:
大学生创新创业训练计划项目（201510075026）

Application with adaptive statistical iterative reconstruction and low radiation in the pulmonary angiography

ZHAO Yongxia¹,², CHANG Jin², ZUO Ziwei², ZHANG Changda², ZHANG Tianle², MENG Bo⁴, LI Dan⁴,ZHANG Linlin⁴, ZHU Changyue⁴, LI Shenglan⁴

1. School of Precision Instrument and Opto-Electronics Engineering,Tianjin University, Tianjin 300000,China；2. Department of Radiology, Affiliated Hospital of Hebei University，Baoding 071000, China; 3. Tianjin University,Tianjin 300000, China; 4. College of Clinical Medicine, Hebei University, Baoding 071000, China

Online:2015-06-25 Published:2015-06-25

摘要/Abstract

摘要： 目的探讨迭代重建算法在肺动脉CT 血管成像（CTPA）低剂量扫描中的临床应用研究。方法将体质量指数为20~25 的150 例患者随机分成5 组进行CTPA 扫描，图像重建算法为ASIR（adaptive statistical iterative reconstruction），扫描范围为260~310 mm，第一组扫描条件为机器默认的120 kV、400 mAs，对图像进行重建并计算信噪比（SNR）及对比度噪声比（CNR），请2 位影像学家对图像进行5 分值主观评价。固定120 kV，用350 mAs 、300 mAs、 250 mAs 及200 mAs 对其他组患者进行扫描，记录不同mAs 的CTDIvol 及DLP，并转换为有效剂量ED。对上述扫描条件下图像进行重建，计算图像的SNR 及CNR，并进行主观评价。结果对120 kV，不同电流（400 mAs ，350 mAs ，300 mAs，250 mAs ，200 mAs）扫描产生的图像进行SNR 及CNR 评价，其值分别为：22.95、22.90、21.82、20.80、20.83 和23.61、22.88、22.86、21.93、21.97。2 位影像学家对120 kV 下400~200 mAs 主观评价分值分别为：4.59±0.32，4.48±0.30，4.82±0.28，4.28±0.36,4.15±0.38；其CTDIvol、DLP 平均值分别为： 13.84 mGy、11.18 mGy、9.31 mGy、8.25 mGy、7.38 mGy 和351.21 mGy 、312.32 mGy 、286.26 mGy 、233.52 mGy 、206.08 mGy，并将DLP 转换为ED 为5.27 mSv 、4.68 mSv、4.29 mSv、3.50 mSv、3.09 mSv。对上述数据进行单因素方差分析，200 mAs、250 mAs、300 mAs、350 mAs 与400 mAs 产生的影像质量没有明显差异（F＝5.285，P＞0.05），但200 mAs 的CTDIvol、DLP 及ED 较400 mAs 分别低46.7%、41.3% 及41.3%。结论体质量指数为20~25 的被检者进行CTPA 检查时最佳扫描条件为120 kV，200 mAs。对于体型较小（肌肉较少）或有肺气肿等疾病可以选用180～200 mAs 进行扫描。

关键词: 迭代重建, 肺动脉CTA, 辐射剂量, 影像质量

Abstract: Objective To investigate the effect of adaptive statistical iterative reconstruction and low radiation on the image quality of CT pulmonary angiography. Methods 150 patients whose body mass index was from 20 to 25 were divided into 5 groups underwent pulmonary angiography on a GE HD 750 CT scanners. The scanning range was from 260mm to 310mm, the first group of scan parameters were 120kV,400mAs, it was the acquiescent parameters of the CT scanner. Reconstruction was performed with ASIR, then the signal to noise ratio (SNR) and contrast to noise ratio(CNR) were calculated. The images of different strength of ASIR were read by 2 independent radiologists with 5-point-scale, then based 120kV, the other group patients were scaned with 350 mAs, 300 mAs, 250 mAs, 200 mAs, recorded the CTDIvol and DLP in different mAs. The effective dose (ED) was calculated based on the DLP, The SNR and CNR were calculated and the image quality were assessed by the two experienced readers. Results The images were assessed under different mAs (400 mAs, 350 mAs, 300 mAs, 250 mAs, 200 mAs) and the 120kV at the strength of 3, the values of the SNR and CNR were 22.95, 22.90, 21.82, 20.80, 20.83 and 23.61, 22.88, 22.86, 21.93, 21.97. The values of from 400 mAs to 200 mAs by two independent radiologists were 4.59±0.32, 4.48±0.30, 4.82±0.28, 4.28±0.36, 4.15±0.38. The CTDIvol and DLP of different mAs (400 mAs,350 mAs, 300 mAs, 250 mAs, 200 mAs) were 13.84 mGy, 11.18 mGy, 9.31 mGy, 8.25 mGy, 7.38 mGy and 351.21 mGy, 312.32 mGy, 286.26 mGy, 233.52 mGy, 206.08 mGy. the ED were 5.27 mSv, 4.68 mSv, 4.29 mSv,3.50 mSv, 3.09 mSv. Statistical analysis was performed using analysis of variance, and the date was not statistically significant(F=5.285, P＞0.05) at the exposure factors of 200 mAs, 250 mAs, 300mAs, 350mAs than 400 mAs, but the CTDIvol and DLP of 200mAs were reduced 46.7% and 41.3%, the ED was reduced 41.3%. respectively than the 400 mAs. Conclusion The best mAs is from 200 mAs for the average person whose BMI is from 20 to 25 in CTPA. For smaller (less muscle) or emphysema and other diseases it can be choosen from 180 mAs to 200 mAs.

Key words: iterative reconstruction, CT pulmonary angiography, radiation dose, image quality

中图分类号:

赵永霞，常津，左紫薇，张畅达，张天乐，孟博，李丹，张琳琳，朱长月，李盛蓝. 迭代重建算法在肺动脉CTA 低剂量扫描中的应用研究[J]. 医学研究与教育, 2015, 32(3): 16-21.

ZHAO Yongxia, CHANG Jin, ZUO Ziwei, ZHANG Changda, ZHANG Tianle, MENG Bo, LI Dan,ZHANG Linlin, ZHU Changyue, LI Shenglan. Application with adaptive statistical iterative reconstruction and low radiation in the pulmonary angiography[J]. Medical Reserch and Education, 2015, 32(3): 16-21.

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迭代重建算法在肺动脉CTA 低剂量扫描中的应用研究

Application with adaptive statistical iterative reconstruction and low radiation in the pulmonary angiography

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