血糖变异性与重症脑出血患者预后的临床研究

doi:10.3969/j.issn.1674-490X.2015.03.005

医学研究与教育 ›› 2015, Vol. 32 ›› Issue (3): 22-25.DOI: 10.3969/j.issn.1674-490X.2015.03.005

血糖变异性与重症脑出血患者预后的临床研究

赵慧新，邸卫英，袁蓓，崔蕾，张杏红，闫奕，宋月平

河北大学附属医院，河北保定 071000

出版日期:2015-06-25 发布日期:2015-06-25
通讯作者: 邸卫英（1974—），女，河北保定人，硕士，副主任医师，主要从事脑血管病及神经重症研究。E-mail: huandeng2004@163.com
作者简介:赵慧新（1978—），女，河北唐山人，硕士，主治医师，主要从事脑血管病研究。
基金资助:
河北省医学适用技术跟踪项目（GL102312）

Clinical study between blood glucose fluctuation and prognosis of severe cerebral hemorrhage patients

ZHAO Huixin, DI Weiying, YUAN Bei, CUI Lei, ZHANG Xinghong, YAN Yi, SONG Yueping

Affiliated Hospital of Hebei University, Baoding 071000, China

Online:2015-06-25 Published:2015-06-25

摘要/Abstract

摘要： 目的探讨血糖变异性与重症脑出血患者预后的关系。方法对河北大学附属医院神经内科58 例重症脑出血患者有无机械通气、住院时间、急性生理与慢性健康评估Ⅱ (APACHE Ⅱ ) 等临床资料进行分析。按预后分为存活组(n=41) 和死亡组(n=17) 两组。记录所有患者的初始血糖值、血糖值、血糖标准差、变异系数，用血糖标准差及变异系数来衡量血糖变异性。探讨血糖变异性与死亡的关系。结果死亡组与存活组比较，有无机械通气、住院时间、APACHE Ⅱ评分差异有统计学意义（P<0.05）。死亡组血糖标准差、变异系数均高于存活组（P<0.05）。结论血糖变异性与重症脑出血患者的预后密切相关。

关键词: 血糖变异性, 脑出血, 死亡

Abstract: Objective To discuss the correlation between blood glucose fluctuation and prognosis of severe cerebral hemorrhage patients. Methods 58 patients with severe cerebral hemorrhage were selected as subjects. The clinical characteristics of all the patients were analyzed，such as mechanical ventilation, days of hospitalization , acute physiology and chronic health evaluation II (APACHE II) score. Those patients were divided into two groups: survival group (n=41) and death group (n=17). Initial blood glucose, blood glucose value, mean number of blood glucose, standard deviation of blood glucose and variation coefficient of blood glucose were recorded. Standard deviation and variation coefficient of blood glucose were used as glucose variability index to explore the correlation between blood glucose fluctuation and death. Results Mechanical ventilation, days of hospitalization, APACHE II score in death group were higher than the control group （P<0.05）. Standard deviation and variation coefficient of blood glucose in death group were significantly higher than that of the survival group（P<0.05）. Conclusion Blood glucose fluctuation and severe cerebral hemorrhage in the patients may be closely correlated with prognosis.

Key words: blood glucose fluctuation, cerebral hemorrhage, death

中图分类号:

赵慧新，邸卫英，袁蓓，崔蕾，张杏红，闫奕，宋月平. 血糖变异性与重症脑出血患者预后的临床研究[J]. 医学研究与教育, 2015, 32(3): 22-25.

ZHAO Huixin, DI Weiying, YUAN Bei, CUI Lei, ZHANG Xinghong, YAN Yi, SONG Yueping. Clinical study between blood glucose fluctuation and prognosis of severe cerebral hemorrhage patients[J]. Medical Reserch and Education, 2015, 32(3): 22-25.

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血糖变异性与重症脑出血患者预后的临床研究

Clinical study between blood glucose fluctuation and prognosis of severe cerebral hemorrhage patients

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