围术期高血糖的发生机制与研究进展

doi:10.3969/j.issn.1674-490X.2016.04.011

医学研究与教育 ›› 2016, Vol. 33 ›› Issue (4): 52-56.DOI: 10.3969/j.issn.1674-490X.2016.04.011

围术期高血糖的发生机制与研究进展

王春亮¹,张乐²,赵海歌¹,王红杰³

1.河北大学医学部, 河北保定 071000;
2.河北省保定市妇幼保健院功能科, 河北保定 071000;
3.河北大学附属医院, 河北保定 071000

收稿日期:2016-05-09 出版日期:2016-08-25 发布日期:2016-08-25
通讯作者: 王红杰(1968—),女,河北保定人,主任医师,博士,主要从事临床麻醉工作。E-mail: hongjiew68@163.com
作者简介:王春亮(1988—),男,河北承德人,医师,在读硕士,主要从事临床麻醉工作。 E-mail: 553536889@qq.com
基金资助:
河北省医学与科学研究重点课题(20160046)

The pathogenesis of perioperative hyperglycemia and research progress

WANG Chunliang¹,ZHANG Le²,ZHAO Haige¹,WANG Hongjie³

1.College of Clinical Medicine, Hebei University, Baoding 071000, China; 2. Department of Function, Maternal and Child Care Service Centre, Baoding 071000, China; 3. Affiliated Hospital of Hebei University, Baoding 071000, China

Received:2016-05-09 Online:2016-08-25 Published:2016-08-25

摘要/Abstract

摘要： 围术期应激性高血糖是机体在严重创伤、麻醉、手术等刺激条件下所产生的一种代谢反应,并被认为是围术期并发症发生和死亡的重要因素。应激性高血糖的发生机制主要和反调节激素的增多、细胞因子的大量释放和胰岛素抵抗有关。针对围术期高血糖的发生机制,从麻醉和强化胰岛素治疗两方面探讨血糖的调控措施。临床上围术期应激性高血糖的治疗应个体化,维持血糖平稳至关重要。

关键词: 围术期, 应激性高血糖, 机制

Abstract: Stress hyperglycemia is a matabolic reaction when the body come across severe trauma、anesthesia、operation and other stress in perioperative.It is also considered an important factor of perioperative complication and death.The mechanism is related to increase counter hormone,release of cytokines and insulin resistance.Because of the mechanism of perioperative hyperglycemia,we discuss the regulation of blood glucose from anesthesia and intensive insulin therapy.The management of stress hyperglycemia should be individualized,it is important to control blood sugar stable.

Key words: perioperative, stress hyperglycemia, mechanism

中图分类号:

R619

王春亮,张乐,赵海歌,王红杰. 围术期高血糖的发生机制与研究进展[J]. 医学研究与教育, 2016, 33(4): 52-56.

WANG Chunliang,ZHANG Le,ZHAO Haige,WANG Hongjie. The pathogenesis of perioperative hyperglycemia and research progress[J]. Medical Reserch and Education, 2016, 33(4): 52-56.

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围术期高血糖的发生机制与研究进展

The pathogenesis of perioperative hyperglycemia and research progress

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