血清胃蛋白酶原、胃泌素17在胃食管反流病诊断中的研究进展

doi:10.3969/j.issn.1674-490X.2018.02.002

医学研究与教育 ›› 2018, Vol. 35 ›› Issue (2): 13-16.DOI: 10.3969/j.issn.1674-490X.2018.02.002

血清胃蛋白酶原、胃泌素17在胃食管反流病诊断中的研究进展

郭会玲,高广周,郝英霞

保定市第一中心医院, 河北保定 071000

收稿日期:2018-01-22 出版日期:2018-04-25 发布日期:2018-04-25
通讯作者: 郝英霞(1964—),女,河北保定人,主任医师,硕士,硕士生导师,主要从事胃食管反流病、消化心身疾病、早期胃癌研究。E-mail: 906452725@qq.com
作者简介:郭会玲(1989—),女,河北邯郸人,医师,在读硕士,主要从事慢性胃炎、胃食管反流病、早期胃癌研究。

Received:2018-01-22 Online:2018-04-25 Published:2018-04-25

摘要/Abstract

摘要： 胃蛋白酶原和胃泌素-17是由胃黏膜的腺体细胞分泌产生,胃蛋白酶原可经胃酸激活为胃蛋白酶,胃泌素-17又可促进胃酸的分泌,胃蛋白酶和胃酸又是胃食管反流病的重要致病因素,二者可经胃黏膜的毛细血管进入到血循环系统。现就血清胃蛋白酶原和胃泌素-17在胃食管反流病中诊断价值的研究进展做一综述。

关键词: 胃蛋白酶原, 胃泌素-17, 胃食管反流病

Abstract: Pepsinogen and gastrin-17 are mainly produced by gastric mucosal gland cells. Pepsinogen can be activated by gastric acid as pepsin. G-17 can also promote the secretion of gastric acid. Gastric acid and pepsin are also the important risk factors of the gastroesophageal reflux disease. Serum pepsinogen and gastrin-17 can enter the blood circulation through the gastric mucosal capillaries. The research progress on the diagnostic value of serum pepsinogen and gastrin-17 in gastroesophageal reflux disease is reviewed.

Key words: pepsinogen, gastrin-17, gastroesophageal reflux disease

中图分类号:

郭会玲,高广周,郝英霞. 血清胃蛋白酶原、胃泌素17在胃食管反流病诊断中的研究进展[J]. 医学研究与教育, 2018, 35(2): 13-16.

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血清胃蛋白酶原、胃泌素17在胃食管反流病诊断中的研究进展

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