Rsf-1在几种常见恶性肿瘤中的表达及意义

doi:10.3969/j.issn.1674-490X.2018.05.003

医学研究与教育 ›› 2018, Vol. 35 ›› Issue (5): 12-18.DOI: 10.3969/j.issn.1674-490X.2018.05.003

Rsf-1在几种常见恶性肿瘤中的表达及意义

张金玉¹,乔树¹,陈保平²

1. 河北大学医学院, 河北保定 071000;
2.河北大学附属医院乳腺外科, 河北保定 071000

收稿日期:2018-07-17 出版日期:2018-10-25 发布日期:2018-10-25
通讯作者: 陈保平(1962—),男,河北保定人,主任医师,硕士,硕士生导师,主要从事消化道、乳腺等恶性肿瘤的研究。E-mail:cbp1962@126.com
作者简介:张金玉(1990—),女,河北保定人,医师,在读硕士,主要从事乳腺肿瘤方面的研究。

Received:2018-07-17 Online:2018-10-25 Published:2018-10-25

摘要/Abstract

摘要： 染色质重塑因子1(Remodeling and spacing factor 1,Rsf-1)也叫做肝炎-BX相关蛋白(hepatities BX-antigen associated protein,HBXAP),在胃癌、肝癌、结肠癌等常见恶性肿瘤中均呈过表达的状态,并且该因子的过表达与恶性肿瘤细胞的增殖和恶性程度相关,高表达Rsf-1的患者往往具有更高的TNM分期、更差的预后。

关键词: 染色质重塑因子1, 恶性肿瘤, 耐药性, 细胞增殖, 侵袭性

Abstract: Chromatin remodeling factor 1(Rsf-1), also known as hepatitis BX-antigen associated protein(HBXAP), is overexpressed in common malignant tumors such as gastric, liver and colon cancer, and its overexpression is associated with the proliferation and malignancy grade of malignant cells. The patients with high Rsf-1 expression tend to have higher TNM stage and poorer prognosis.

Key words: Rsf-1, malignant tumor, drug resistance, cell proliferation, invasiveness

中图分类号:

张金玉,乔树,陈保平. Rsf-1在几种常见恶性肿瘤中的表达及意义[J]. 医学研究与教育, 2018, 35(5): 12-18.

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Rsf-1在几种常见恶性肿瘤中的表达及意义

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