中老年人群外周血压水平与臂踝脉搏波传导速度的关系

doi:10.3969/j.issn.1674-490X.2019.06.002

摘要/Abstract

摘要： 目的探讨中老人群外周血压(SBP、DBP、MAP、PP)水平与臂踝脉搏波传导速度(baPWV)的关系。方法在开滦集团职工体检中随机分层抽取5 852人作为研究对象,符合入选标准(年龄≥40岁,既往无脑卒中、短暂性脑缺血发作、心肌梗死)且资料完整的4 937人纳入分析。采用多因素线性回归分析SBP、DBP、MAP和PP水平对baPWV的影响。结果(1)4 937(男2 959,女1 978)例平均年龄(51.24±11.43)岁,平均SBP为(126.93±19.34)mmHg,平均DBP为(81.19±10.92)mmHg,平均MAP为(96.44±12.88)mmHg,平均PP为(45.78±13.20)mmHg。2010年至2011年体检时平均baPWV为1 578.02 cm/s。(2)SBP、DBP、MAP、PP与baPWV均呈正相关(r分别为0.501、0.269、0.403和0.508,均P<0.001)。(3)多因素线性回归分析显示校正相同混杂因素后,SBP、DBP、MAP、PP每升高一个标准差,baPWV分别增加91.59(82.12~101.06)cm/s、59.57(50.68~68.46)cm/s、78.62(69.48~87.76)cm/s和77.15(67.51~86.80)cm/s(均P<0.001)。(4)在男/女性人群及不同年龄阶段(40~49岁,50~59岁,≥60岁)人群中,结果均与总人群结果一致。结论 SBP、DBP、MAP和PP增加均与baPWV增加独立正相关。

关键词: 收缩压, 舒张压, 平均动脉压, 脉压, 臂踝脉搏波传导速度

Abstract: Objective To investigate the relationship between peripheral blood pressure and brachial-ankle pulse wave velocity(baPWV)in middle-aged and old population. Methods A total of 5 852 participants was selected with stratified random sampling from the 101 510 workers of Tangshan Kailuan company who received the health examination. 4 937 participants with integral data were in accordance with the inclusion criteria(age of 40+ years without history of stroke and coronary heart disease)and were recruited into the survey. Multivariate linear regression analysis was used to analyze the influence of peripheral blood pressure on baPWV. Results(1)Among 4 937 participants(2 959 men and 1 978 women)with an average age of 51.24 years old, their mean of SBP, DBP, MAP and PP were(126.93±19.34)mmHg,(81.19±10.92)mmHg,(96.44±12.88)mmHg and(45.78±13.20 )mmHg, respectively. Mean baPWV was(1 578.02±391.76)cm/s and was greater in man than women(P<0.001).(2)baPWV were positively related to SBP, DBP, MAP and PP, were 0.501, 0.269, 0.403 and 0.508, respectively(all P<0.001).(3)Multiple logistic regression analysis showed that after adjusting for age and other risk factors, for 1 SD of peripheral systolic BP SBP, DBP, MAP and PP, baPWV increased 91.59(82.12~101.06)cm/s, 59.57(50.68~68.46)cm/s, 78.62(69.48~87.76)cm/s and 77.15(67.51~86.80)cm/s, respectively(all P<0.001).(4)The results were consistent after stratified by sex and age. Conclusion Higher SBP, DBP, MAP and PP are positively associated with increasing baPWV in middle-aged and old population.

Key words: systolic blood pressure, diastolic blood pressure, mean arterial pressure, pulse pressure, brachial-ankle pulse wave velocity

中图分类号:

陶杰,张永强,许巧玲,姚海珍,甄利波. 中老年人群外周血压水平与臂踝脉搏波传导速度的关系[J]. 医学研究与教育, 2019, 36(6): 8-14.

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