医学研究与教育 ›› 2014, Vol. 31 ›› Issue (1): 79-82.DOI: 10.3969/j.issn.1674-490X.2014.01.018

• 综述 • 上一篇    下一篇

NK细胞杀伤弓形虫的机制及中药的调节作用

吴丹,肖蓓蕾,李晓东,王斐然,杨漠源,王伟强   

  1. 河北大学医学部,河北 保定,071000
  • 收稿日期:2016-09-29 修回日期:2016-09-29 出版日期:2014-02-25 发布日期:2014-02-25

The mechanisms of NK cells in killing Toxoplasma gondii and the role of traditional Chinese medicine in its regulation

WU Dan,XIAO Beilei,LI Xiaodong,WANG Feiran,YANG Moyuan,WANG Weiqiang   

  • Received:2016-09-29 Revised:2016-09-29 Online:2014-02-25 Published:2014-02-25

摘要: NK细胞的杀伤活性无MHC限制,不依赖抗体,其靶细胞主要是某些肿瘤细胞、病毒感染细胞、某些自身组织细胞、寄生虫等,所以在抗细胞内弓形虫感染的免疫应答中起重要作用,将影响 NK 细胞杀伤弓形虫活性的中药成分以及NK细胞杀伤弓形虫的机制等进行综述。

关键词: 弓形虫, NK细胞, 感染, 中药成分, 杀伤

Abstract: The killing activity of NK cells, whose main target cells are some tumor cells, cells infected by virus, tissue cells and parasites, etc, has no MHC restriction, and does not rely on antibody, so it plays an important role in the immune response to toxoplasma infection in cells. The following will review the Chinese herb ingredient which affects the activity of NK cells to kill toxoplasma and the mechanisms of NK cell in killing Toxoplasma gondii.

Key words: Toxoplasma gondii, NK cells, infection, Chinese native medicine ingredient, killing

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