医学研究与教育 ›› 2018, Vol. 35 ›› Issue (2): 37-44.DOI: 10.3969/j.issn.1674-490X.2018.02.006

• 中医药学 • 上一篇    下一篇

基于医案数据研究萎缩性胃炎的辨证及组方规律

曹海燕,刘琛,李远,全晨阳,车若梅,蒙丽君,佟红娜   

  1. 河北大学中医学院, 河北 保定 071000
  • 收稿日期:2018-01-24 出版日期:2018-04-25 发布日期:2018-04-25
  • 通讯作者: 李远(1975—),男,重庆人,副教授,博士,主要从事名老中医临床经验的系统研究。E-mail: liyuancdutcm@126.com
  • 作者简介:曹海燕(1995—),女,河北张家口人。

  • Received:2018-01-24 Online:2018-04-25 Published:2018-04-25

摘要: 目的 通过研究慢性萎缩性胃炎的中医医案,总结整理出中医治疗慢性萎缩性胃炎的辨证以及组方规律。方法 收集治疗慢性萎缩性胃炎的相关中医医案,运用数据分析法、聚类算法以及关联规则分析等多种研究方法,整理有效数据并总结概括出中医治疗慢性萎缩性胃炎的辨证和组方用药规律。结果 本研究通过分析252份萎缩性胃炎的相关中医医案,对医案中常见的证候、具体治法、使用较高频次的中药及药物配伍间的关联规则高度概括,最终得出32个核心配伍及14个新处方。结论 中医治疗慢性萎缩性胃炎在证型、具体治法、治疗用药等多个方面有一定规律可循,因此,借助转化医学的分析方法和医案数据挖掘技术得出的萎缩性胃炎的治疗规律具有一定的可行性及临床参考价值。

关键词: 慢性萎缩性胃炎, 关联规则, 辨证组方, 转化医学

Abstract: Objective To study the dialectical and formula of traditional Chinese medicine for treating chronic atrophic gastritis by studying the Chinese medicine case of chronic atrophic gastritis. Methods A collection of traditional Chinese medical records in the treatment of chronic atrophic gastritis was used. Data analysis, clustering algorithms, and association rules analysis were used to summarize the available data and summarize the dialectical and prescription medications in the treatment of chronic atrophic gastritis in traditional Chinese medicine law. Results 252 Chinese medicine cases related to atrophic gastritis were analyzed, and the common syndromes, specific treatment methods of how to use higher frequency Chinese herbal medicines, and association rules of drug compatibility among medical records were summarized. 32 core compatibility of medicines and 14 new prescriptions were discovered. Conclusion The treatment of chronic atrophic gastritis with Chinese medicine has certain rules to follow in syndrome differentiation, specific treatment, and medication. Therefore, the therapeutic law of atrophic gastritis obtained by means of analytical methods of translational medicine and data mining techniques of medical recordshas a certain degree of feasibility and clinical reference value.

Key words: chronic atrophic gastritis, association rules, dialectical group, translational medicine

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