脓毒性休克液体复苏的最新研究进展

doi:10.3969/j.issn.1674-490X.2024.05.002

摘要/Abstract

摘要： 脓毒性休克是在脓毒症的基础上,感染进行性加重,出现血流动力学不稳定,经充分液体复苏后仍出现低血压,而无其他低血压原因可循。作为脓毒性休克治疗的关键,液体复苏是治疗脓毒性休克的初始环节及基石,其旨在增加心输出量和改善组织氧合。总结与论述液体复苏的生理学机制、复苏液体类型、液体复苏剂量及液体复苏监测指标等方面的最新研究进展,以期加深对脓毒性休克及其液体复苏策略的认识,为脓毒性休克的临床救治与基础研究提供参考和借鉴。

关键词: 脓毒性休克, 液体复苏, 液体管理, 治疗, 预后

Abstract: Septic shock is a disease based on sepsis, with progressive aggravation of infection, hemodynamic instability, hypotension after adequate fluid resuscitation, and no other cause of hypotension to follow. Fluid resuscitation plays an important role in the treatment of septic shock, which is the initial step and cornerstone of the treatment of septic shock. It aims to increase cardiac output and improve tissue oxygenation. This paper summarizes and discusses the latest research developments in the physiological mechanism, type of resuscitation fluid, dose of resuscitation fluid and monitoring indicators of resuscitation fluid, in order to deepen the understanding of septic shock and its liquid resuscitation strategy, and provide reference for the clinical treatment and research of septic shock.

Key words: septic shock, fluid resuscitation, liquid management, treatment, prognosis

中图分类号:

张和荟, 刘彦权, 王芬, 陈淑娟, 许庆林. 脓毒性休克液体复苏的最新研究进展[J]. 医学研究与教育, 2024, 41(5): 11-18.

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