新型肥胖指标与2型糖尿病肾病的相关性分析

doi:10.3969/j.issn.1674-490X.2025.03.002

摘要/Abstract

摘要： 目的探讨新型肥胖指标,如脂质蓄积指数(lipid accumulation product, LAP)、身体圆度指数(body roundness index, BRI)、内脏脂肪指数(visceral adiposity index, VAI),与2型糖尿病肾病(type 2 diabetes nephropathy, T2DN)的关系,以指导临床工作。方法以承德市中心医院内分泌科收集297例病例为基础,采用Logistic回归分析新型肥胖指标与T2DN的关联性。结果本研究共有297例患者被纳入。单因素分析结果显示,BRI、LAP、VAI与T2DN有相关性(P<0.05)。多因素Logistic回归分析表明,调整混杂因素后,BRI与T2DN呈正相关(OR=3.121,95%CI=1.877~5.190)。结论 BRI是T2DN的独立危险因素。

关键词: 内脏脂肪指数, 脂质蓄积指数, 身体圆度指数, 2型糖尿病肾病

Abstract: Objective To investigate the relationship between novel obesity indicators, such as lipid accumulation product(LAP), body roundness index(BRI), visceral adiposity index(VAI)and type 2 diabetes nephropathy(T2DN), to guide clinical work. Methods Based on 297 cases collected from the Department of Endocrinology of Chengde City Central Hospital, the association between the novel obesity index and T2DN was analyzed by Logistic regression. Results A total of 297 patients were included in this study.The results of the univariate analysis showed that BRI, LAP, and VAI were correlated with T2DN(P<0.05). Multifactorial logistic regression analysis showed that BRI was positively associated with T2DN as an independent risk factor after adjusting for confounding factors(OR=3.121, 95%CI=1.877~5.190). Conclusion BRI is an independent risk factor for T2DN.

Key words: visceral adiposity index, lipid accumulation product, body roundness index, type 2 diabetes nephropathy

中图分类号:

陈曼玉,侯奥飞,刘丹. 新型肥胖指标与2型糖尿病肾病的相关性分析[J]. 医学研究与教育, 2025, 42(3): 8-15.

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