Study on the preparation and stability of the lysozyme-stabilized silver nanoparticles

doi:10.3969/j.issn.1674-490X.2014.04.001

Abstract

Abstract: Objective We have synthesized silver nanoparticles using protein as the stabilizer and discussed their stability to provide theoretical guidance for their application in biomedical ifeld and daily life. Methods We have presented a one-step approach of chemical reduction to prepare the lysozyme-stabilized silver nanoparticles. Results The stability of lysozyme-stabilized silver nanoparticles was sensitive to the change of ionic strength and the nanoparticles precipitated completely in 10 mmol/L NaCl. The lysozyme-stabilized silver nanoparticles were stable under acidic condition (pH≤6). And the freeze-thawing cycle had a little inlfuence on their stability. Conclusion The stability of lysozyme-stabilized silver nanoparticles is greatly inlfuenced by the surrounding conditions. The variation caused by the stability factors should be considered for use and storage of the lysozyme-stabilized silver nanoparticles.

Key words: silver nanoparticles, lysozyme, stability

CLC Number:

O648

ZHAO Yali,YANG Tao,ZHANG Ying,GAO Hongyun,XI Yanan. Study on the preparation and stability of the lysozyme-stabilized silver nanoparticles[J]. Medical Reserch and Education, 2014, 31(4): 1-7,19.

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