Abstract: Objective To explore the clinical effects of Sanjie Snalgesic capsule and mirena in the treatment of uterine adenomyosis. Methods The patients with uterine adenomyosis in our hospital were collected at random,and they were treated with mifepristone, mirena, Sanjie Snalgesic capsule and mirena. The degree of dysmenorrheal, uterine volume, HGB, serum CA125 level of the three groups before and after 3 months treatment were observed. Results After 3 months treatment, the symptoms of three groups were improved effectively. All patients were amenorrhea.The degree of dysmenorrheal, uterine volume, serum CA125 level of the mirena, Sanjie Snalgesic capsule and mirena groups were signiifcantly lower than those in the mifepristone group, otherwise the level of HGB was significantly higher. The degree of dysmenorrheal, uterine volume, serum CA125 level of the Sanjie Snalgesic capsule and mirena group was signiifcantly lower than those in the mirena group. Conclusion The Sanjie Snalgesic capsule and mirena has a good synergy effect in treating uterine adenomyosis, it can improve the clinical effects, reduce the adverse reaction of using myopathy, it is worthy of clinical popularization.

Key words: Sanjie Snalgesic capsule, Mirena, uterine adenomyosis, clinical effect, adverse reaction