doi:10.3969/j.issn.1674-490X.2018.02.002

Abstract

Abstract: Pepsinogen and gastrin-17 are mainly produced by gastric mucosal gland cells. Pepsinogen can be activated by gastric acid as pepsin. G-17 can also promote the secretion of gastric acid. Gastric acid and pepsin are also the important risk factors of the gastroesophageal reflux disease. Serum pepsinogen and gastrin-17 can enter the blood circulation through the gastric mucosal capillaries. The research progress on the diagnostic value of serum pepsinogen and gastrin-17 in gastroesophageal reflux disease is reviewed.

Key words: pepsinogen, gastrin-17, gastroesophageal reflux disease

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References

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