Abstract: Objective To investigate the clinical value of quantitative susceptibility mapping(QSM)in cerebral microbleeds(CMBs). Methods 122 patients with cerebrovascular disease were enrolled in the routine MRI sequence including T1,T2,T2FLAIR sequences and SWI and QSM sequence imaging. All patients underwent a CT scan of the head within one week. The patients were examined,successfully,the number of microbleeds in the basal ganglia and the area outside the basal ganglia were obtained,and the corresponding statistical analysis was performed. Results Of the 122 patients with cerebrovascular disease,80 had cerebral microbleeds and 42 were not detected. A total of 481 microbleeds were detected. Among them,481 cerebral microbleeds were detected in the QSM sequence. 447 cerebral microbleeds were detected,and the total detection rate of CMBs was statistically significant(P<0.05). The difference between the two groups in the detection of CMBs in each region was statistically significant(P<0.05). Conclusion The detection rate of CMBs in QSM sequences is better than that in SWI sequences,which is an accurate and reliable imaging method for diagnosing CMBs.

Key words: magnetic resonance imaging, quantitative susceptibility mapping, susceptibility weighted imaging, cerebral microbleeds