Abstract: Objective To analyze the risk factors associated with recurrence in patients with benign paroxysmal positional vertigo(BPPV)and provide targeted prevention of recurrence of BPPV and improve the quality of life of patients. Methods The medical records of 255 patients with BPPV who were admitted to the Department of Otolaryngology, Affiliated Hospital of Hebei University from January, 2018 to January, 2019 were collected. All patients successfully completed manual reduction treatment. Gender, age, frequency of incidence and previous medical history(including hypertension, diabetes, hyperlipidemia, sleep quality, etc.)of all patients were recorded in detail. All patients' hospital anxiety and depression scale(HADS)scores were recorded to assess whether they had anxiety or(and)depression, and serum calcium ion concentration and serum homocysteine(HCY)concentration were recorded. The recurrence of BPPV patients was recorded in clinical or telephone follow-up for 1 year. The baseline data of patients in the relapsing group and the non-relapsing group were analyzed and compared. The risk factors of BPPV recurrence were analyzed by multiple linear regression. Results After strict inclusion and exclusion criteria, a total of 255 patients with BPPV were included in this study, and all patients completed the manual repositioning and were followed up clinically or by telephone for 1 year, 31 patients were lost, and a total of 224 patients completed the follow-up, including 52 patients in the recurrence group and 172 patients in the non-recurrence group, with a recurrence rate of about 23.2%. By comparing the two groups by one-way ANOVA, the differences were not statistically significant(P>0.05)for gender, age, hyperlipidemia, and blood calcium concentration, and statistically significant(P<0.05)for hypertensive disease, diabetes, sleep quality, anxiety or(and)depression, and blood HCY concentration. Further binary logistic regression analysis revealed that anxiety or(and)depression was an independent risk factor for recurrence in patients with BPPV. Conclusion Anxiety and/or depression are closely related to BPPV recurrence.

Key words: benign paroxysmal positional vertigo, recurrence, risk factors

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