doi:10.3969/j.issn.1674-490X.2021.01.007

Abstract

Abstract: Objective To analyze the prevalence and related risk factors of fatty liver disease in a population undergoing physical examination in Xi'an city and provide basis for targeted prevention and treatment of fatty liver in the future. Methods 9 096 healthy adults who had physical examination with complete clinical records in Xi'an No.3 hospital were enrolled, identified with FLD. At the same time, anthropometry, biochemical immune indicators and disease history were collected, and the disease status was studied with age and gender stratification. Data analysis was performed using the χ² test, t-test, and logistic regression analysis. Results Among the 9 096 cases, a total of 2 290 cases of FLD were detected with ultrasound examination, with a prevalence rate of 25.18%. The prevalence was significantly higher in males than that in females(P<0.01). The prevalence was highest in females aged 60-69 years(22.67%)and highest in males aged 30-39 years(41.29%). The mean levels of body mass index, total cholesterol, triglyceride, low-density lipoprotein, fasting blood glucose, blood uric acid, systolic blood pressure and diastolic blood pressure in the fatty liver group were significantly higher than those in the non-fatty liver group, while the high-density lipoprotein was significantly lower than those in the non-fatty liver group(P<0.01). Multivariate logistic regression analysis showed that age, body mass index, diastolic blood pressure, fasting blood glucose, triglyceride, total cholesterol, blood uric acid, gallbladder disease were risk factors for fatty liver. Conclusion The prevalence of FLD is higher in males than in females among the physical examination population in xi'an city. Overweight and obesity, dyslipidemia, hypertension, hyperglycemia, hyperuricemia and gallbladder disease were the main risk factors.

Key words: fatty liver, prevalence, risk factors, metabolic disorders

CLC Number:

R195.4

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