Abstract: Objective To analyze the risk factors for the occurrence of preterm small for gestational age infant(SGA)infants, and to provide a basis for targeted strengthening of perinatal education and clinical intervention. Methods From January 2017 to January 2022, 1 483 preterm infants admitted to the neonatology department of the Affiliated Hospital of Hebei University were selected for the study. The study subjects were divided into two groups according to the relationship between birth mass and gestational age, namely preterm small for gestational age infant(SGA)group and appropriate for gestational age infant(AGA)group, and the perinatal risk factors of each group were analyzed. The risk factors for preterm SGA were analysed using univariate and multifactorial logistic regression. Results A higher proportion of mothers in the preterm SGA group with a combination of hypertensive disorders of pregnancy, low amniotic fluid, placental abnormalities, anaemia during pregnancy, multiple pregnancies, advanced maternal age and undergoing assisted reproductive technology relative to the preterm AGA group, with a statistically significant difference(P<0.05). The results of logistic regression analysis showed that mothers with hypertensive disorders during pregnancy, placental abnormalities, and anemia during pregnancy were independent risk factors for the occurrence of SGA(P<0.05). Conclusion Mothers with hypertensive disorders in pregnancy, placental abnormalities, and anaemia in pregnancy are closely related to the occurrence of SGA in preterm labour. In clinical work, targeted perinatal education and timely intervention should be carried out to reduce the incidence of SGA.

Key words: children with intrauterine growth retardation, small for gestational age infant, appropriate for gestational age infant, premature babies, high risk factors