doi:10.3969/j.issn.1674-490X.2024.03.003

Abstract

Abstract: Coronary heart disease is the most common cause of death in the elderly. The incidence of frailty in elderly patients is significantly increased. Frailty assessment can well predict the prognosis of elderly patients with coronary heart disease. However, the mechanism of frailty leading to poor prognosis of coronary heart disease is not very clear. Studies have shown that intestinal flora may play an important role in patients with frailty and coronary heart disease. In recent years, due to the advancement of gene sequencing technology, the correlation between intestinal flora and frailty in the elderly has become clearer. The main purposes of this review are to explain the important role of intestinal flora in the occurrence and development of patients with frailty and coronary heart disease by analyzing the relationship between intestinal flora and frailty through early intervention of intestinal flora in patients with frailty to achieve the purpose of preventing adverse cardiovascular events and in order to provide a theoretical basis for clinical secondary prevention of patients with coronary heart disease.

Key words: coronary heart disease, frailty, intestinal microbiome, frailty assessment

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References

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