Abstract: Objectiv To evaluate the sensitivity of heart-type fatty acid-binding protein (H-FABP) and ischaemia modified albumin (IMA) in acute myocardial infarction (AMI) and compare theirs diagnostic efficacy in early stage AMI. Methods The creteria pulished by Chinese society of cardiology at December, 2001 was taken as the golden standard. H-FABP and IMA were measured in AMI patients at 2 h, 3 h, 6 h, 9 h, 24 h after the onset of chest pain, and the efficacy of these index were evaluated. Results At 2 h after chest pain, the sensitivity rate of H-FABP was 62.7%, the sensitivity of IMA was 76.5%. At 3 h after chest pain, the sensitivity rate of H-FABP was 82.4%, the sensitivity of IMA was 86.3%. At 6 h after chest pain, the sensitivity rate of H-FABP was 84.3%, the sensitivity of IMA was 80.4%. At 9 h after chest pain, the sensitivity rate of H-FABP was 64.7%, the sensitivity of IMA was 54.9%. At 24 h after chest pain, the sensitivity rate of H-FABP was 37.3%, the sensitivity of IMA was 23.5%. conclusion The sensitivity of H-FABP and IMA is high.

Key words: acute myocardial infarction, early diagnosis, H-FABP, IMA, sensitivity